Evidence map›Paper›PMID 34845507›Full record

Trial reportSurgery today2022

Risk factors for postoperative proximal deep vein thrombosis and pulmonary embolism after laparoscopic colorectal cancer surgery: analysis of a multicenter randomized controlled trial.

Masayoshi Yasui, Masataka Ikeda, Taishi Hata, Shu Okamura, Yasuhiro Miyake, Hideki Sakisaka, Hidekazu Takahashi, Norikatsu Miyoshi, Mamoru Uemura, Tsunekazu Mizushima and 5 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgery today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Establishment and Validation of a Postoperative VTE Prediction Model in Patients with Colorectal Cancer Undergoing Radical Resection: CRSPOT Nomogram.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Masayoshi YasuiDepartment of Gastroenterological Surgery, Osaka International Cancer Institute, Otemae 3-1-69, Chuo-ku, Osaka, Japan. myasui-gi@umin.ac.jp.ORCID http://orcid.org/0000-0001-6391-3630
Masataka IkedaDepartment of Surgery, Osaka National Hospital, Osaka, Japan.
Taishi HataDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Shu OkamuraDepartment of Surgery, Suita Municipal Hospital, Suita, Japan.
Yasuhiro MiyakeDepartment of Surgery, Nishinomiya Municipal Central Hospital, Nishinomiya, Japan.
Hideki SakisakaDepartment of Surgery, Kawanishi City Hospital, Kawanishi, Japan.
Hidekazu TakahashiDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Norikatsu MiyoshiDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Mamoru UemuraDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Tsunekazu MizushimaDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Hirofumi YamamotoDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Kohei MurataDepartment of Surgery, Suita Municipal Hospital, Suita, Japan.
Yuichiro DokiDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan.
Clinical Study Group of Osaka University (CSGO), Colorectal Group
The University of Osaka · JPKansai Rosai Hospital · JPHyogo Medical University · JPKishiwada City Hospital · JPNishinomiya Municipal Central Hospital · JPOsaka International Cancer Institute · JPSuita Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePostoperative venous thromboembolism (VTE) is a major and potentially fatal postoperative complication of colorectal cancer surgery. However, there is uncertainty about the necessity for anticoagulant prophylaxis to prevent VTE after laparoscopic colorectal cancer surgery because of its associated relatively lower incidence. Currently, anticoagulant therapy is considered mainly for patients at high risk of the development of VTE. Focusing on proximal deep vein thrombosis (DVT)/ pulmonary embolism (PE), we aimed to identify those cases at high risk of the development of fatal VTE.

methodsWe performed an exploratory retrospective analysis to identify the risk factors for postoperative proximal DVT and PE after laparoscopic colorectal cancer surgery in patients included in our prospective trial.

resultsA logistic regression analysis revealed factors that could predict the onset of proximal DVT/PE in patients with colorectal cancer. Blood loss and tumor location were identified as the predictors of proximal DVT/PE.

conclusionsPatients with rectal cancer and those with excessive blood loss during colon cancer surgery must be monitored carefully for signs of VTE and especially proximal DVT/PE, after laparoscopic surgery.

Indexed as

Colorectal NeoplasmsLaparoscopyPulmonary EmbolismVenous ThromboembolismVenous ThrombosisAnticoagulantsHumansPostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsAnticoagulantsColorectal cancerLaparoscopic surgeryProphylaxisVenous thromboembolism

Identifiers

PMID34845507
OpenAlexW3215720364

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.