Evidence map›Paper›PMID 34845295›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2022

The effects of maternal hypertension on the early neonatal platelet count.

Peter Joslyn, Cornelius Rosenbaum, Andrew G Chapple, Asha Heard, Maria Velez, Brian Barkemeyer

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Peter JoslynDepartment of Pediatrics Division of Neonatology, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA. pjosly@lsuhsc.edu.ORCID http://orcid.org/0000-0003-4636-4283
Cornelius RosenbaumBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Andrew G ChappleBiostatistics Program, School of Public Health, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Asha HeardDepartment of Obstetrics and Gynecology Division of Maternal Fetal Medicine, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Maria VelezDepartment of Pediatrics Division of Hematology Oncology, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.
Brian BarkemeyerDepartment of Pediatrics Division of Neonatology, Louisiana State University Health Sciences Center New Orleans, New Orleans, LA, USA.ORCID http://orcid.org/0000-0002-7762-4415
Louisiana State University Health Sciences Center New Orleans · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the relationship between maternal hypertension and early neonatal platelet counts. STUDY

designThis single site retrospective cohort study compared initial platelet counts in the first day of life of infants born to mothers with preeclampsia with severe features (PSF) (n = 224) and infants born to normotensive mothers using multivariable logistic and Quasi-Poisson regression models.

resultThere was no statistical difference in initial platelet counts or likelihood of thrombocytopenia (aOR = 1.19, 95% CI 0.68-2.08) between infants born to mothers with PSF and infants born to normotensive mothers after multivariable adjustment. Initial platelet counts and thrombocytopenia risk were unaffected by the presence of maternal end organ dysfunction. Small for gestational age (SGA) status was the most significant risk factor for the development of thrombocytopenia (aOR = 2.24, 95% CI 1.13-4.30).

conclusionMaternal PSF does not directly affect neonatal initial platelet counts. SGA status confers the greatest risk of early thrombocytopenia.

Indexed as

HypertensionInfant, Newborn, DiseasesPre-EclampsiaThrombocytopeniaFemaleHumansInfantInfant, NewbornPlatelet CountPregnancyRetrospective Studies

Identifiers

PMID34845295
OpenAlexW3216509100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.