Evidence map›Paper›PMID 34845196›Full record

ArticleCell discovery2021

Depletion of giant ANK2 in monkeys causes drastic brain volume loss.

Dong-Dong Qin, Jian-Kui Zhou, Xie-Chao He, Xiang-Yu Shen, Cong Li, Huan-Zhi Chen, Lan-Zhen Yan, Zheng-Fei Hu, Xiang Li, Long-Bao Lv and 5 more

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Longitudinal Characterization of GiantResearch (Washington, D.C.) · 2026
    Article
  4. Article
  5. Reappraisal ofReviews in cardiovascular medicine · 2025
    Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Dong-Dong Qin *Key Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Jian-Kui Zhou *Precise Genome Engineering Center, School of Life Sciences, Guangzhou University, Guangzhou, Guangdong, China.
Xie-Chao He *Primate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Xiang-Yu Shen *Institute of Neuroscience, State Key Laboratory of Neuroscience, Chinese Academy of Sciences, Shanghai, China.
Cong LiState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Huan-Zhi ChenKey Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Lan-Zhen YanPrimate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Zheng-Fei HuPrimate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Xiang LiPrimate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Long-Bao LvPrimate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.
Yong-Gang YaoKey Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. yaoyg@mail.kiz.ac.cn.ORCID http://orcid.org/0000-0002-2955-0693
Zheng WangKey Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. zheng.wang@ion.ac.cn.ORCID http://orcid.org/0000-0001-7138-8581
Xing-Xu HuangSchool of Life Science and Technology, Shanghai Tech University, Shanghai, China. huangxx@shanghaitech.edu.cn.ORCID http://orcid.org/0000-0001-8934-1247
Xin-Tian HuKey Laboratory of Animal Models and Human Disease Mechanisms, Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. xthu@mail.kiz.ac.cn.
Ping ZhengPrimate Facility, National Research Facility for Phenotypic & Genetic Analysis of Model Animals, and National Resource Center for Non-Human Primates, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. zhengp@mail.kiz.ac.cn.ORCID http://orcid.org/0000-0003-0402-5507
Kunming Institute of Zoology · CNChinese Academy of Sciences · CNGuangzhou University · CNKunming Institute of Botany · CNShanghaiTech University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 31730037, U1702284, 31771174, 31960178, 81941014, 81771387, 31800901
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID34845196
PMCPMC8629971
OpenAlexW3216945167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.