Evidence map›Paper›PMID 34845187›Full record

ArticleBlood cancer journal2021

MPL S505C enhances driver mutations at W515 in essential thrombocythemia.

Leila N Varghese, Gonzalo Carreño-Tarragona, Gabriel Levy, Xabier Gutiérrez-López de Ocáriz, Inmaculada Rapado, Joaquín Martínez-López, Rosa Ayala, Stefan N Constantinescu

Open access · goldAbstract readCase ReportsLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Leila N Varghese *Université Catholique de Louvain and de Duve Institute, Brussels, Belgium.
Gonzalo Carreño-Tarragona *Haematology and Haemotherapy Department, Hospital Universitario 12 de Octubre, I+12, CNIO, Complutense University, CIBERONC, Madrid, Spain.ORCID 0000-0002-9570-5542
Gabriel LevyUniversité Catholique de Louvain and de Duve Institute, Brussels, Belgium.ORCID 0000-0001-6746-3083
Xabier Gutiérrez-López de OcárizHaematology and Haemotherapy Department, Hospital Universitario 12 de Octubre, I+12, CNIO, Complutense University, CIBERONC, Madrid, Spain.
Inmaculada RapadoHaematology and Haemotherapy Department, Hospital Universitario 12 de Octubre, I+12, CNIO, Complutense University, CIBERONC, Madrid, Spain.
Joaquín Martínez-LópezHaematology and Haemotherapy Department, Hospital Universitario 12 de Octubre, I+12, CNIO, Complutense University, CIBERONC, Madrid, Spain.
Rosa AyalaHaematology and Haemotherapy Department, Hospital Universitario 12 de Octubre, I+12, CNIO, Complutense University, CIBERONC, Madrid, Spain. rosam.ayala@salud.madrid.org.ORCID 0000-0002-2699-8353
Stefan N ConstantinescuUniversité Catholique de Louvain and de Duve Institute, Brussels, Belgium. stefan.constantinescu@bru.licr.org.ORCID 0000-0002-8599-2699
Hospital Universitario 12 De Octubre · ESLudwig Cancer Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissenseAged, 80 and overAmino Acid SubstitutionFemaleHumansReceptors, ThrombopoietinThrombocythemia, EssentialMPL protein, humanReceptors, Thrombopoietin

Identifiers

PMID34845187
PMCPMC8630145
OpenAlexW3216076523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.