Evidence map›Paper›PMID 34844629›Full record

ArticleJournal of nanobiotechnology2021

Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy.

Suresh Kumar Chakkarapani, Tae Hwan Shin, Seungah Lee, Kyung-Soo Park, Gwang Lee, Seong Ho Kang

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Diesel-derived PMFrontiers in endocrinology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Suresh Kumar Chakkarapani *Department of Chemistry, Graduate School, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea.
Tae Hwan Shin *Department of Physiology, Ajou University School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea.
Seungah Lee *Department of Applied Chemistry and Institute of Natural Sciences, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea.
Kyung-Soo ParkNanophotonics Research Center, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Gwang LeeDepartment of Physiology, Ajou University School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea. glee@ajou.ac.kr.ORCID http://orcid.org/0000-0002-1299-9478
Seong Ho KangDepartment of Chemistry, Graduate School, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea. shkang@khu.ac.kr.ORCID http://orcid.org/0000-0003-2101-4113
Kyung Hee University · KRAjou University · KRKorea Institute of Science and Technology · KR

Funding

ministry of education 2019R1A2C12002556ministry of science and ict (kr) 2020R1A4A4079722
6 · The paper itself

Abstract

backgroundNanoparticles have been used for biomedical applications, including drug delivery, diagnosis, and imaging based on their unique properties derived from small size and large surface-to-volume ratio. However, concerns regarding unexpected toxicity due to the localization of nanoparticles in the cells are growing. Herein, we quantified the number of cell-internalized nanoparticles and monitored their cellular localization, which are critical factors for biomedical applications of nanoparticles.

methodsThis study investigates the intracellular trafficking of silica-coated magnetic nanoparticles containing rhodamine B isothiocyanate dye [MNPs@SiO

resultsThe MNPs@SiO

conclusionThe sensitive and quantitative evaluations of MNPs@SiO

Indexed as

Magnetite NanoparticlesSilicon DioxideAnimalsBiological TransportHEK293 CellsHumansImage Processing, Computer-AssistedIntracellular SpaceMiceMicroscopyNIH 3T3 CellsRAW 264.7 CellsSingle-Cell AnalysisMagnetite NanoparticlesSilicon DioxideLive cell analysisMagnetic nanoparticleMicroarraySingle-particle trackingSuper-resolution microscopy

Identifiers

PMID34844629
PMCPMC8628397
OpenAlexW3216691829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.