Evidence map›Paper›PMID 34844443›Full record

ArticleThe American surgeon2023

Safety and Clinical Value of Prophylactic Ureteral Stenting Before Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy.

David N Hanna, Andrew Hermina, Emma Bradley, Muhammad O Ghani, Alexander Mina, Christina E Bailey, Kamran Idrees, Deepa Magge

Open access · greenAbstract read
In one paragraph

Article in The American surgeon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David N HannaVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.ORCID 0000-0003-2530-0328
Andrew HerminaMeharry Medical College, Nashville, TN, USA.
Emma BradleyVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.
Muhammad O GhaniVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.
Alexander MinaVanderbilt University School of Medicine, Nashville, TN, USA.
Christina E BaileyVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.
Kamran IdreesVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.
Deepa MaggeVanderbilt University Medical Center, Section of Surgical Sciences, Division of Surgical Oncology and Endocrine Surgery, Nashville, TN, USA.
Vanderbilt University Medical Center · USMeharry Medical College · USVanderbilt University · US

Funding

Surgical Oncology Training GrantT32CA106183 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI James Richard Goldenring · 2004 to 2026
$6.0M
NCI NIH HHS T32 CA106183
6 · The paper itself

Abstract

backgroundProphylactic ureteral stents (PUS) are typically placed prior to complex abdominal or pelvic operations at the surgeon's discretion to help facilitate detection of iatrogenic ureteral injury. However, its usefulness and safety in the setting of cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) have not been examined. This study aims to evaluate the potential clinical value and risk profile of prophylactic ureteral stent placement prior to CRS-HIPEC.

methodsWe performed a single-institutional retrospective analysis of 145 patients who underwent CRS-HIPEC from 2013 to 2021. Demographic and operative characteristics were compared between patients who underwent PUS placement and those that did not. Ureteral stent-related complications were evaluated.

resultsOf the 145 patients included in the analysis, 124 underwent PUS placement. There were no significant differences in patient demographics, medical comorbidities, or tumor characteristics. Additionally, PUS placement did not significantly increase operative time and was not associated with increased pelvic organ resection. However, patients who underwent prophylactic ureteral stenting had significantly higher peritoneal carcinomatosis index score (15.1 vs 9.1, P

conclusionProphylactic ureteral stent placement in patients undergoing CRS-HIPEC may be useful, particularly in patients with predetermined extensive pelvic disease. However, PUS placement is not without potential morbidity and should be selectively considered in patients for whom benefits outweigh the risks.

Indexed as

Hyperthermia, InducedPeritoneal NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, Cancer, Regional PerfusionCombined Modality TherapyCytoreduction Surgical ProceduresHumansHyperthermic Intraperitoneal ChemotherapyRetrospective StudiesStentsSurvival Rate

Identifiers

PMID34844443
PMCPMC9149136
OpenAlexW3217037653

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.