Evidence map›Paper›PMID 34844314›Full record

SynthesisThe Science of the total environment2022

Effectiveness of interventions for the remediation of lead-contaminated soil to prevent or reduce lead exposure - A systematic review.

Andreea-Iulia Dobrescu, Agnes Ebenberger, Julia Harlfinger, Ursula Griebler, Irma Klerings, Barbara Nußbaumer-Streit, Andrea Chapman, Lisa Affengruber, Gerald Gartlehner

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in The Science of the total environment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Andreea-Iulia DobrescuDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria. Electronic address: andreea.dobrescu@donau-uni.ac.at.
Agnes EbenbergerDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Julia HarlfingerDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Ursula GrieblerDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Irma KleringsDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Barbara Nußbaumer-StreitDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Andrea ChapmanDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Lisa AffengruberDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria.
Gerald GartlehnerDepartment for Evidence-based Medicine and Evaluation, Danube University Krems, Krems a.d. Donau, Austria; RTI International, Research Triangle Park, NC, USA.
Universität für Weiterbildung Krems · ATRTI International · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo summarize the evidence on the effectiveness of soil remediation to prevent or reduce lead exposure.

methodsWe systematically searched MEDLINE, the Agricultural & Environmental Science Database, Web of Science, and Scopus from 1980 to February 15, 2021. We also performed reference list checking, hand-searched websites, and contacted experts. Eligible studies evaluated the effect of soil remediation to prevent or reduce lead exposure in humans of any age. We screened all records dually; one investigator performed the data extraction; a second checked for completeness and accuracy. Two investigators independently rated the risk of bias of included studies and graded the certainty of evidence. We synthesized findings narratively.

resultsWe identified 6614 potentially relevant publications, all focused on children, of which five studies (six records) fulfilled our prespecified inclusion criteria. The number of evaluated participants ranged from 31 to 1425, with follow-up periods of 11 months to one year. The primary soil remediation method was the replacement of the upper layer with clean soil. Outcomes were limited to blood lead levels (BLL), dust lead levels, and soil lead levels. The largest study, a controlled before- after study (n = 1425) reported favorable effects of soil remediation compared to no intervention. This finding was consistent with results from two cross-sectional studies and one uncontrolled before-after study. One year post-remediation, the mean reduction in BLL was 2.1 μg/dL (p < 0.0001) greater in the intervention group than in the control group. Two randomized controlled trials with a total of 511 participants showed no statistically significant incremental effect of soil remediation when combined with paint and/or dust abatement. The certainty of evidence for all outcomes was low.

conclusionSoil remediation appears to reduce BLL in children when used as a single intervention. The incremental benefit of soil remediation when part of other interventions is limited.

Indexed as

LeadLead PoisoningChildCross-Sectional StudiesEnvironmental ExposureHumansSoilLeadSoilBlood lead levelChildrenLeadSoil remediation

Identifiers

PMID34844314
PMCPMC8655614
OpenAlexW3201121768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.