ArticleAmerican journal of ophthalmology2022
Advanced OCT Analysis of Biopsy-proven Vitreoretinal Lymphoma.
Article in American journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Multimodal imaging for diagnosis and follow-up of primary vitreoretinal lymphoma: A systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Pooled it
- Spectrally Resolved (Colour-Coded) Fundus Autofluorescence Using the EIDON System in Vitreoretinal Lymphoma.Ophthalmology and therapy · 2026Article
- Ocular Glymphatic System: Its Modulation and Role in Intraocular Tumors.Investigative ophthalmology & visual science · 2026Review
- Ocular Imaging in Intraocular Lymphoma: A Review.Clinical & experimental ophthalmology · 2026Review
- Optical coherence tomography features and visual prognosis in vitreoretinal lymphoma: a structured phenotyping study.Frontiers in medicine · 2026Article
- SS-OCT/OCTA Assessment of Choroidal Structure in Vitreoretinal Lymphoma Patients and Their Changes During Intravitreal Methotrexate Chemotherapy.Translational vision science & technology · 2025Article
- Clinical guidelines for the diagnosis and treatment of vitreoretinal lymphoma in Chinese patients (2024).Eye and vision (London, England) · 2025Review
- Retromode imaging in vitreoretinal lymphoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Intraocular Lymphoma: A Review.Journal of ophthalmic & vision research · 2025Review
- A comprehensive overview of diagnosis, imaging and treatment of vitreoretinal lymphoma.European journal of ophthalmology · 2024Review
- Optical coherence tomography features in vitreoretinal lymphoma compared with non-infectious uveitis.BMC ophthalmology · 2024Article
- Multimodal imaging in a case of presumed secondary vitreoretinal lymphoma presenting with inner retina and optic nerve head infiltration.American journal of ophthalmology case reports · 2024Article
- Fundus autofluorescence in uveitis: from pathogenesis to imaging interpretation.International ophthalmology · 2023Review
- Optical Density Ratio of Subretinal Fluid in Choroidal Melanomas Versus Choroidal Naevi Assessed by Optical Coherence Tomography.Investigative ophthalmology & visual science · 2023Article
- Artificial Intelligence-Assisted Processing of Anterior Segment OCT Images in the Diagnosis of Vitreoretinal Lymphoma.Diagnostics (Basel, Switzerland) · 2023Article
- Logistic regression models of cytokines in differentiating vitreoretinal lymphoma from uveitis.Journal of clinical laboratory analysis · 2022Article
- Retinal changes of primary vitreoretinal lymphoma after intravitreal methotrexate.BMC ophthalmology · 2022Article
- Research progress on the application of optical coherence tomography in the field of oncology.Frontiers in oncology · 2022Review
- Optical coherence tomography and optical coherence tomography angiography in systemic disease.Taiwan journal of ophthalmologyReview
Corrections and comments
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Authors and funding
20 authors at 12 institutions in 6 countries.
Funding
Abstract
purposeAlthough diagnosing vitreoretinal lymphoma (VRL) can be challenging, early detection is critical for visual prognosis. We analyzed the spectrum of optical coherence tomography (OCT) findings in patients with biopsy-proven VRL and correlate these features with clinical parameters.
designThis retrospective cross-sectional study was a multicenter chart review from 13 retina, uveitis, and ocular oncology clinics worldwide from 2008 to 2019. We included patients with a diagnosis of biopsy-proven VRL imaged with OCT at presentation. Ocular information, systemic information, and multimodal retinal imaging findings were collected and studied. The main outcome measure was the characteristics of VRL on OCT.
resultsA total of 182 eyes of 115 patients (63 women, mean age 65 years) were included in this study. The disease was bilateral in 81 patients (70%), and mean baseline visual acuity was 0.2 ± 0.89 logMAR (Snellen equivalent, 20/32). At baseline, 38 patients (33%) presented with isolated ocular involvement, 54 (45%) with associated central nervous system involvement, and 11 (10%) with other systemic lymphomatous involvement; an additional 12 patients (10%) presented with central nervous system and other systemic involvement. On OCT, tumor infiltration was identified in various retinal layers, including lesions in the subretinal pigment epithelium compartment (91% of eyes), the subretinal compartment (43% of eyes), and the intraretinal compartment (7% of eyes). OCT analysis of eyes with VRL identified 3 main regions of retinal infiltration. Subretinal pigment epithelium location, with or without subretinal infiltration, was the most common pattern of involvement and isolated intraretinal infiltration was the least.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.