Evidence map›Paper›PMID 34843576›Full record

Observational studyPloS one2021

Age-related changes of color visual acuity in normal eyes.

Sho Yokoyama, Yoshiki Tanaka, Takashi Kojima, Rie Horai, Yukihito Kato, Hideki Nakamura, Hiroyuki Sato, Mari Mitamura, Kiyoshi Tanaka, Kazuo Ichikawa

Abstract readObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sho YokoyamaDepartment of Ophthalmology, Japan Community Healthcare Organization Chukyo Hospital, Nagoya, Japan.
Yoshiki TanakaChukyo Eye Clinic, Nagoya, Japan.
Takashi KojimaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Rie HoraiChukyo Eye Clinic, Nagoya, Japan.
Yukihito KatoChukyo Eye Clinic, Nagoya, Japan.
Hideki NakamuraMeito Eye Clinic, Nagoya, Japan.
Hiroyuki SatoSatoh Yuya Eye Clinic, Sendai, Japan.
Mari MitamuraChukyo Eye Clinic, Nagoya, Japan.
Kiyoshi TanakaFaculty of Engineering, Shinshu University, Nagano, Japan.
Kazuo IchikawaChukyo Eye Clinic, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the age-related change in color visual acuity (CVA) in normal eyes.

methodsIn total, 162 normal eyes (162 subjects, women: 52, men: 110, age range: 15-68 years) with best-corrected visual acuity (BCVA) ≥20/13 were enrolled. Fifteen colors from the New Color Test (chroma 6) were applied to Landolt "C" rings, white point D65 was applied as background, and a luminance of 30 cd/m2 was set for both the rings and the background. These rings were used to measure the chromatic spatial discrimination acuity as the CVA value, while changing the stimulus size. Correlations of the CVA value of each color and age were evaluated. Mean CVA values of all 15 colors (logarithm of the minimum angle of resolution) were compared between age groups in 10-year increments.

resultsNine CVA values (red, yellow-red, red-yellow, green, blue-green, green-blue, purple, red-purple, and purple-red) were negatively correlated with age (all p<0.05); the remaining six (yellow, green-yellow, yellow-green, blue, purple-blue, and blue-purple), as well as BCVA were not. The age groups with the best to worst mean CVA values of 15 colors were as follows: 20-29 (mean ± standard deviation, 0.303 ± 0.113), 30-39 (0.324 ± 0.096), 10-19 (0.333 ± 0.022), 50-59 (0.335 ± 0.078), 40-49 (0.339 ± 0.096), and 60-69 (0.379 ± 0.125) years. There were statistically significant differences between mean CVA values of the following groups: 20-29 and 40-49 years; 20-29 and 60-69 years; 30-39 and 60-69 years (all p<0.01).

conclusionsThe CVA values related to the medium/long-wavelength-sensitive cones were more susceptible to aging than those related to the short-wavelength-sensitive cones. This differed from previous reports, and may be related to the difference in the range of foveal cone function evaluated with each examination.

Indexed as

AgingColor VisionVisual AcuityAdolescentAdultAgedFemaleHumansMaleMiddle AgedOcular Physiological PhenomenaProspective StudiesRetinal Cone Photoreceptor CellsVision, OcularYoung Adult

Identifiers

PMID34843576
PMCPMC8629265

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.