Evidence map›Paper›PMID 34843269›Full record

ArticleJournal of psychopathology and clinical science2022

Delay discounting in suicidal behavior: Myopic preference or inconsistent valuation?

Aliona Tsypes, Katalin Szanto, Jeffrey A Bridge, Vanessa M Brown, John G Keilp, Alexandre Y Dombrovski

Abstract read
In one paragraph

Article in Journal of psychopathology and clinical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review: Suicide and its relationship to aggression and impulsivity.Cognitive, affective & behavioral neuroscience · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Leveraging Decision Science to Characterize Depression.Current directions in psychological science · 2023
    Article
  14. Review
  15. Anhedonia and Suicide.Current topics in behavioral neurosciences · 2022
    Review
  16. Review
  17. Social Disconnection in Late Life Suicide: An NIMH Workshop on State of the Research in Identifying Mechanisms, Treatment Targets, and Interventions.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aliona TsypesDepartment of Psychiatry.ORCID 0000-0001-5424-069X
Katalin SzantoDepartment of Psychiatry.
Jeffrey A BridgeAbigail Wexner Research Institute.ORCID 0000-0003-3726-8978
Vanessa M BrownDepartment of Psychiatry.ORCID 0000-0003-0968-1095
John G KeilpDepartment of Psychiatry.
Alexandre Y DombrovskiDepartment of Psychiatry.ORCID 0000-0002-2054-4772

Funding

PSYCHOBIOLOGY OF SUICIDAL BEHAVIOR IN BPDR01MH048463 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 1992 to 2026
$13.9M
Short Term Variability in Affect and Rest Activity Rhythms in Long Term Chronic and Highly Variable Suicidal Ideation in Depressed Older AdultsR01MH085651 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HANGA CSILLA GALFALVY, Swathi Gujral · 2010 to 2026
$9.6M
Roles of Gray Matter Brain Aging and Small Vessel Disease in AD PathophysiologyRF1AG025516 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AIZENSTEIN, HOWARD J, VILLEMAGNE, VICTOR LUIS · 2014 to 2021
$9.0M
CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
Reward Learning in Late-Life Suicidal BehaviorR01MH100095 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Alexandre Y. Dombrovski · 2014 to 2026
$6.8M
CLINICAL RESEARCH TRAINING FOR PSYCHOLOGISTST32MH018269 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHELE D LEVINE · 1986 to 2026
$6.3M
NIA NIH HHS RF1 AG025516NIH HHSNIMH NIH HHS R01 MH048463NIMH NIH HHS R01 MH085651NIMH NIH HHS R01 MH100095NIMH NIH HHS T32 MH018269NIMH NIH HHS T32 MH019986
6 · The paper itself

Abstract

Prior studies sought to explain the predisposition to suicidal behavior in terms of myopic preference for immediate versus delayed reward, generating mixed evidence. Data from gambling and bandit tasks, however, suggest that suboptimal decisions in suicidal individuals are explained by inconsistent valuation rather than myopic preferences. We tested these two alternative hypotheses using a delay discounting task in 622 adults (suicide attempters with depression, suicide ideators with depression, nonsuicidal participants with depression, and healthy controls) recruited across three sites through inpatient psychiatric units, mood disorders clinics, primary care, and advertisements. Multilevel models revealed group differences in valuation consistencies in all three samples, with high-lethality suicide attempters exhibiting less consistent valuation than all other groups in Samples 1 and 3 and less consistent valuation than the healthy controls or participants with depression in Sample 2. In contrast, group differences in preference for immediate versus delayed reward were observed only in Sample 1 and were due to the high-lethality suicide attempters displaying a weaker preference for immediate reward than low-lethality suicide attempters. The findings were robust to confounds such as cognitive functioning and comorbidities. Seemingly impulsive choices in suicidal behavior are explained by inconsistent reward valuation rather than a true preference for immediate reward. In a suicidal crisis, this inconsistency may result in a misestimation of the value of suicide relative to constructive alternatives and deterrents. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

Delay DiscountingSuicidal IdeationAdultHumansImpulsive BehaviorRewardSuicide, Attempted

Identifiers

PMID34843269
PMCPMC8893041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.