Evidence map›Paper›PMID 34843221›Full record

ArticleBiochemistry2021

Identification of an Intermediate Species along the Nitrile Hydratase Reaction Pathway by EPR Spectroscopy.

Wasantha Lankathilaka Karunagala Pathiranage, Natalie Gumataotao, Adam T Fiedler, Richard C Holz, Brian Bennett

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wasantha Lankathilaka Karunagala PathiranageDepartment of Chemistry, Marquette University, 1414 West Clybourn Street, Milwaukee, Wisconsin 53233, United States.
Natalie GumataotaoDepartment of Chemistry and Biochemistry, Loyola University, 1068 West Sheridan Road, Chicago, Illinois 60660, United States.
Adam T FiedlerDepartment of Chemistry, Marquette University, 1414 West Clybourn Street, Milwaukee, Wisconsin 53233, United States.ORCID 0000-0002-6114-8557
Richard C HolzDepartment of Chemistry, Marquette University, 1414 West Clybourn Street, Milwaukee, Wisconsin 53233, United States.ORCID 0000-0001-6093-2799
Brian BennettDepartment of Physics, Marquette University, 1420 West Clybourn Street, Milwaukee, Wisconsin 53233, United States.ORCID 0000-0003-2688-1478
Marquette University · USLoyola University Chicago · US

Funding

Synthetic, Spectroscopic, and Computational Investigations of Thiol Oxidation by Nonheme Iron EnzymesR15GM126522 · NIGMS · MARQUETTE UNIVERSITY · PI FIEDLER, ADAM T · 2017 to 2025
$1.0M
NIGMS NIH HHS R15 GM126522
6 · The paper itself

Abstract

A new method to trap catalytic intermediate species was employed with Fe-type nitrile hydratase from

Indexed as

AcetonitrilesBacterial ProteinsBiocatalysisCatalytic DomainCold TemperatureDeep Eutectic SolventsDensity Functional TheoryElectron Spin Resonance SpectroscopyEscherichia coliGene ExpressionHydrogen-Ion ConcentrationHydro-LyasesIronKineticsNitrilesProtein SubunitsacetonitrileAcetonitrilesBacterial ProteinsbenzonitrileDeep Eutectic SolventsHydro-LyasesIronnitrile hydrataseNitrilesProtein SubunitsRecombinant ProteinsSodium ChlorideWater

Identifiers

PMID34843221
PMCPMC8721871
OpenAlexW3214893008

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.