Evidence map›Paper›PMID 34843164›Full record

ArticleMicrobial biotechnology2022

Metabolic engineering of Vibrio natriegens for anaerobic succinate production.

Felix Thoma, Clarissa Schulze, Carolina Gutierrez-Coto, Maurice Hädrich, Janine Huber, Christoph Gunkel, Rebecca Thoma, Bastian Blombach

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 40 citations in OpenAlex.

  1. Metabolic engineering ofSynthetic and systems biotechnology · 2026
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  4. Applied and environmental microbiology · 2026
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  11. Article
  12. Ploidy inGenes · 2023
    Review
  13. Article
  14. Rapid, high-titer biosynthesis of melanin using the marine bacteriumFrontiers in bioengineering and biotechnology · 2023
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Felix ThomaMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.ORCID 0000-0002-2457-1057
Clarissa SchulzeMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Carolina Gutierrez-CotoMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Maurice HädrichMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Janine HuberMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Christoph GunkelMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Rebecca ThomaMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.
Bastian BlombachMicrobial Biotechnology, Campus Straubing for Biotechnology and Sustainability, Technical University of Munich, Uferstraße 53, Straubing, 94315, Germany.ORCID 0000-0002-2996-2049
Technical University of Munich · DEStadtwerke Straubing (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biotechnological production of succinate bears serious potential to fully replace existing petrochemical approaches in the future. In order to establish an economically viable bioprocess, obtaining high titre, yield and productivity is of central importance. In this study, we present a straightforward engineering approach for anaerobic succinate production with Vibrio natriegens, consisting of essential metabolic engineering and optimization of process conditions. The final producer strain V. natriegens Δlldh Δdldh Δpfl Δald Δdns::pyc

Indexed as

Metabolic EngineeringVibrioAnaerobiosisSuccinic AcidSuccinic Acid

Identifiers

PMID34843164
PMCPMC9151343
OpenAlexW3217739716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.