Evidence map›Paper›PMID 34843114›Full record

ArticleMagnetic resonance in medicine2022

Whole-brain steady-state CEST at 3 T using MR Multitasking.

Pei Han, Karandeep Cheema, Hsu-Lei Lee, Zhengwei Zhou, Tianle Cao, Sen Ma, Nan Wang, Hui Han, Anthony G Christodoulou, Debiao Li

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Study of Power Equivalent Continuous Approximation Based on the Recent Consensus Recommendations for Brain Tumor Imaging with Pulsed Chemical Exchange Saturation Transfer at 3T.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Free-breathing 3D CEST MRI of human liver at 3.0 T.Magnetic resonance in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pei HanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-8532-9339
Karandeep CheemaBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Hsu-Lei LeeBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Zhengwei ZhouBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Tianle CaoBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0003-3739-3103
Sen MaBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-9715-7706
Nan WangBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-7616-8083
Hui HanBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Anthony G ChristodoulouBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0002-9334-8684
Debiao LiBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.

Funding

Quantitative Multiparametric MRI to Assess the Effect of Stem Cell Therapy on Chronic Low Back PainR01AR066517 · NIAMS · CEDARS-SINAI MEDICAL CENTER · PI LI, DEBIAO · 2014 to 2024
$5.3M
Motion-Resolved, Comprehensive Quantitative Tissue Characterization Using MR MultitaskingR01EB028146 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI CHRISTODOULOU, ANTHONY G, LI, DEBIAO · 2019 to 2022
$2.5M
NIAMS NIH HHS R01 AR066517NIBIB NIH HHS R01 EB028146NIH HHS R01 AR066517
6 · The paper itself

Abstract

purposeTo perform fast 3D steady-state CEST (ss-CEST) imaging using MR Multitasking.

methodsA continuous acquisition sequence with repetitive ss-CEST modules was developed. Each ss-CEST module contains a single-lobe Gaussian saturation pulse, followed by a spoiler gradient and eight FLASH readouts (one "training line" + seven "imaging lines"). Three-dimensional Cartesian encoding was used for k-space acquisition. Reconstructed CEST images were quantified with four-pool Lorentzian fitting.

resultsSteady-state CEST with whole-brain coverage was performed in 5.6 s per saturation frequency offset at the spatial resolution of 1.7 × 1.7 × 3.0 mm

conclusionThree-dimensional ss-CEST with whole-brain coverage can be done at 3 T within 5.5 min using MR Multitasking.

Indexed as

BrainMagnetic Resonance ImagingNormal DistributionAPTchemical exchange saturation transferMR MultitaskingrNOEsteady-state CEST

Identifiers

PMID34843114
PMCPMC9242691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.