Evidence map›Paper›PMID 34843101›Full record

ArticleAging clinical and experimental research2022

Incidence and risk factors associated with surgical site infection after surgically treated hip fractures in older adults: a retrospective cohort study.

Pei Du, Yanbin Zhu, Junfei Guo, Sufen Qi, Jin Qin, Cuiying Zheng, Zhiyong Hou, Yingze Zhang, Qing-Bao Tian, Zhongjun Feng

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Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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  5. Balancing risks in febrile hip fracture patients: is surgical delay more dangerous than infection?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pei Du *Department of Epidemiology and Statistics, Hebei Key Laboratory of Environment and Human Health, School of Public Health, Hebei Medical University, Shijiazhuang, China.
Yanbin Zhu *Department of Orthopaedics Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Junfei Guo *Department of Orthopaedics Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Sufen QiDepartment of Social Medicine, School of Public Health, Hebei Medical University, Shijiazhuang, China.
Jin QinHebei Orthopedic Clinical Research Center, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Cuiying ZhengDepartment of Bacteriology, The Third Hospital of Hebei Medical University, Shijiazhuang, China.
Zhiyong HouDepartment of Orthopaedics Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Yingze ZhangDepartment of Orthopaedics Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Qing-Bao TianDepartment of Epidemiology and Statistics, Hebei Key Laboratory of Environment and Human Health, School of Public Health, Hebei Medical University, Shijiazhuang, China. tqb1980@hebmu.edu.cn.
Zhongjun FengDepartment of Infection Control and Prevention, The Third Hospital of Hebei Medical University, Shijiazhuang, China. fzjdoc@163.com.
Third Hospital of Hebei Medical University · CNHebei Medical University · CN

Funding

the Medical Science Research Project of Hebei Province 20201008
6 · The paper itself

Abstract

backgroundSurgical site infection (SSI) is one of the most common complications in the traumatic orthopedics field, but remains not adequately studied after hip fractures.

aimsThis study aims to investigate the incidence and risk factors associated with SSI after surgically treated hip fractures in older adults.

methodsA retrospective cohort study including 2932 older adult patients (1416 with femoral neck fracture and 1516 with intertrochanteric fracture) surgically treated from Jan 2015 to Dec 2019 due to hip fractures was performed. Their data on demographics, injury-related data, surgery-related data, and preoperative laboratory test results were collected from hospitalization medical records. Univariate analyses were used to compare between the patients with and without SSI, and multivariate logistic regression analyses were used to identify the risk factors.

resultsA total of 89 patients developed SSI, with an accumulated incidence rate of 3.04% (95%CI 2.41-3.66). Staphylococcus aureus was the most common source of infection. In univariate analysis, 11 items were found to be significant in femoral neck fractures and 5 items were found to be significant in intertrochanteric fracture. In the multivariable logistic regression model, cerebrovascular disease (OR 2.17, 95%CI 1.14-4.15) and hematocrit (HCT) (< Lower limit) (OR 3.46, 95%CI 1.13-10.56) were independent risk factors for SSI in femoral neck fracture. Heart disease (OR 2.13, 95%CI 1.18-3.85) was a risk factor for SSI, while LDH (> 250 U/L) (OR 0.44, 95%CI 0.20-0.95) was a protective factor for SSI in intertrochanteric fracture. DISCUSSION: We observed 89 cases (3.04%) of SSI in 2932 older adult patients with hip fractures in this study. Cerebrovascular disease and lower HCT were two independent risk factors for SSI in femoral neck fracture, whereas heart disease was a risk factor and LDH was a protective factor for SSI in intertrochanteric fracture.

conclusionsTargeted preoperative management, such as predicting the probability of SSI and taking appropriate measures accordingly is essential and highly regarded. Future multicentric studies with more patients evaluated are expected to better address the risk factors for SSI in older hip fracture patients.

Indexed as

Femoral Neck FracturesHeart DiseasesHip FracturesAgedHumansIncidenceRetrospective StudiesRisk FactorsSurgical Wound InfectionHip fracturesIncidenceOlder adultsRisk factorsSurgical site infection

Identifiers

PMID34843101
OpenAlexW3217190634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.