ReviewJapanese journal of radiology2022
Subchondral insufficiency fracture of the knee: review of current concepts and radiological differential diagnoses.
Review in Japanese journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Comparison of the efficacy of Oxford unicondylar replacement for the treatment of spontaneous osteonecrosis of the knee versus medial knee osteoarthritis: a meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Artificial Intelligence-Based Prediction of Prognosis After Nonsurgical Treatment for Medial Meniscus Posterior Root Tear.Orthopaedic journal of sports medicine · 2026Article
- Article
- Subchondral bone abnormalities in the knee: imaging techniques, regional anatomy, and pathology.Skeletal radiology · 2026Review
- Medial femoral condyle bone mineral density is associated with subchondral insufficiency fractures in female patients with medial meniscus posterior root tears.Journal of experimental orthopaedics · 2026Article
- Subchondral Knee Injections: A Comprehensive Systematic Review of Current Clinical Outcomes, Safety, and Arthroplasty Delay.Cartilage · 2026Article
- [Research advances on subchondral insufficiency fracture and osteonecrosis of the knee].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Patients with preoperative bone marrow oedema benefit more substantially from medial meniscus posterior root repair.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- [Subchondral insufficiency fractures of the knee : Navigating the complex terminology landscape].Radiologie (Heidelberg, Germany) · 2026Review
- Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee.Arthritis research & therapy · 2026Article
- Subchondral Insufficiency Fracture of the Knee Previously Diagnosed as Spontaneous Osteonecrosis: A Case Report With Histological Analysis.Case reports in orthopedics · 2026Article
- Utility of Quantitative and Semi-Quantitative SPECT/CT Metrics in Differentiating Mueller-Weiss Syndrome.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- MRI versus radiography as eligibility screening tool for knee osteoarthritis clinical trials: Data from the osteoarthritis initiative.Seminars in arthritis and rheumatism · 2025Article
- Histopathological evaluation of spontaneous osteonecrosis of the knee: time to reconsider history and nomenclature-a scoping review.Musculoskeletal surgery · 2025Article
- [Bone marrow edema and osteonecrosis in sport : Relevance, prognosis and therapy].Orthopadie (Heidelberg, Germany) · 2025Review
- [Etiology of osteonecrosis and bone marrow edema].Orthopadie (Heidelberg, Germany) · 2025Review
- Subchondral insufficiency fracture of the knee.Orthopadie (Heidelberg, Germany) · 2025Review
- Prevalence of Clinically Relevant Findings on Magnetic Resonance Imaging in Middle-Aged Adults With Knee Pain and Suspected Meniscal Tear: A Follow-Up.Arthritis care & research · 2025Article
- Transient osteoporosis of the knee in pregnancy: A case report and literature review.Radiology case reports · 2025Article
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5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Subchondral insufficiency fracture of the knee (SIFK) is a common cause of knee joint pain in older adults. SIFK is a type of stress fracture that occurs when repetitive and excessive stress is applied to the subchondral bone. If the fracture does not heal, the lesion develops into osteonecrosis and results in osteochondral collapse, requiring surgical management. Because of these clinical features, SIFK was initially termed "spontaneous osteonecrosis of the knee (SONK)" in the pre-MRI era. SONK is now categorized as an advanced SIFK lesion in the spectrum of this disease, and some authors believe the term "SONK" is a misnomer. MRI plays a significant role in the early diagnosis of SIFK. A subchondral T2 hypointense line of the affected condyle with extended bone marrow edema-like signal intensity are characteristic findings on MRI. The large lesion size and the presence of osteochondral collapse on imaging are associated with an increased risk of osteoarthritis. However, bone marrow edema-like signal intensity and osteochondral collapse alone are not specific to SIFK, and other osteochondral lesions, including avascular necrosis, osteochondral dissecans, and osteoarthritis should be considered. Chondral lesions and meniscal abnormalities, including posterior root tears, are also found in many patients with SIFK, and they are considered to be related to the development of SIFK. We review the clinical and imaging findings, including the anatomy and terminology history of SIFK, as well as its differential diagnoses. Radiologists should be familiar with these imaging features and clinical presentations for appropriate management.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.