ArticleMedical & biological engineering & computing2022
Determination of anisotropic elastic parameters from morphological parameters of cancellous bone for osteoporotic lumbar spine.
Article in Medical & biological engineering & computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- The Relationship Between Magnetic Resonance Diffusion Tensor Imaging Parameters and Muscle Dysfunction in Patients with Osteoporosis: A Cross-Sectional Retrospective Study.International journal of general medicine · 2026Article
- Analysis of biomechanical load cases for the investigation of pedicle screws ASTM F1717 vs. Toggling.Frontiers in bioengineering and biotechnology · 2026Article
- Functionally Graded Lattice (FGL) Models for Predicting the Mechanical Properties of Femur Spongy Bone.Biomedical engineering and computational biology · 2026Article
- Morphological characteristics of lumbar vertebral bodies and regional distribution patterns of bone mineral density: a CT study.Frontiers in physiology · 2026Article
- Approach to Standardized Material Characterization of the Human Lumbopelvic System: Testing and Evaluation.Bioengineering (Basel, Switzerland) · 2025Article
- Analysis of Biomechanical Characteristics of Bone Tissues Using a Bayesian Neural Network: A Narrative Review.Journal of functional biomaterials · 2025Review
- A data-driven framework for developing a unified density-modulus relationship for the human lumbar vertebral body.Journal of the mechanical behavior of biomedical materials · 2025Article
- Effect of trabecular architectures on the mechanical response in osteoporotic and healthy human bone.Medical & biological engineering & computing · 2024Article
- A simple projection method to correlate the principal mechanical direction with the principal microstructural direction of human osteoporotic femoral heads.Medical & biological engineering & computing · 2024Article
- Bone Mineral Density Prediction from CT Image: A Novel Approach using ANN.Applied bionics and biomechanics · 2023Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
In biomechanics, large finite element models with macroscopic representation of several bones or joints are necessary to analyze implant failure mechanisms. In order to handle large simulation models of human bone, it is crucial to homogenize the trabecular structure regarding the mechanical behavior without losing information about the realistic material properties. Accordingly, morphology and fabric measurements of 60 vertebral cancellous bone samples from three osteoporotic lumbar spines were performed on the basis of X-ray microtomography (μCT) images to determine anisotropic elastic parameters as a function of bone density in the area of pedicle screw anchorage. The fabric tensor was mapped in cubic bone volumes by a 3D mean-intercept-length method. Fabric measurements resulted in a high degree of anisotropy (DA = 0.554). For the Young's and shear moduli as a function of bone volume fraction (BV/TV, bone volume/total volume), an individually fit function was determined and high correlations were found (97.3 ≤ R
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