Evidence map›Paper›PMID 34842841›Full record

ReviewTropical medicine and infectious disease2021

Systemic, Mucosal, and Memory Immune Responses following Cholera.

Edward T Ryan, Daniel T Leung, Owen Jensen, Ana A Weil, Taufiqur Rahman Bhuiyan, Ashraful Islam Khan, Fahima Chowdhury, Regina C LaRocque, Jason B Harris, Stephen B Calderwood and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Long-Term Kinetics of Serological Antibodies againstInternational journal of environmental research and public health · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Edward T RyanDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.
Daniel T LeungDivision of Infectious Diseases, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Owen JensenDivision of Infectious Diseases, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT 84132, USA.
Ana A WeilDivision of Allergy and Infectious Diseases, University of Washington, Seattle, WA 98109, USA.
Taufiqur Rahman BhuiyanInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.
Ashraful Islam KhanInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.
Fahima ChowdhuryInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.
Regina C LaRocqueDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0003-4558-0339
Jason B HarrisDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.
Stephen B CalderwoodDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-2083-7153
Firdausi QadriInternational Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka 1212, Bangladesh.
Richelle C CharlesDivision of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID 0000-0002-8881-1849
Harvard University · USInternational Centre for Diarrhoeal Disease Research · BDUniversity of Utah · USMassachusetts General Hospital · USUniversity of Washington · US

Funding

Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
O-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1M
Antibody mediated protective immunity against choleraR01AI137164 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHARLES, RICHELLE C, HARRIS, JASON B · 2018 to 2022
$3.9M
O-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7M
Estimating Cholera Burden with Cross-sectional Immunologic DataR01AI135115 · NIAID · UNIVERSITY OF UTAH · PI LEUNG, DANIEL TED · 2018 to 2022
$3.4M
Mucosal associated invariant T (MAIT) cells in Vibrio cholerae infection and vaccinationR01AI130378 · NIAID · UNIVERSITY OF UTAH · PI LEUNG, DANIEL TED · 2017 to 2021
$1.8M
Cross-disciplinary Training in Immunology, Inflammation and Infectious DiseaseT32AI138945 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Tracey Jane Lamb, Matthew A Williams · 2018 to 2026
$1.6M
The gut microbiome and susceptibility to Vibrio choleraeK08AI123494 · NIAID · UNIVERSITY OF WASHINGTON · PI WEIL, ANA A · 2016 to 2020
$967k
O-Specific Polysaccharide Responses and CholeraR56AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2013 to 2020
$843k
Humoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359k
FIC NIH HHS D43 TW005572FIC NIH HHS TW005572FIC NIH HHS TW010362National Institute of Allergy and Infectious Diseases AI106878National Institute of Allergy and Infectious Diseases AI130378National Institute of Allergy and Infectious Diseases AI135115National Institute of Allergy and Infectious Diseases AI137164NIAID NIH HHS K08 AI123494NIAID NIH HHS R01 AI130378NIAID NIH HHS R01 AI135115NIAID NIH HHS R01 AI137164NIAID NIH HHS R37 AI106878NIAID NIH HHS T32 AI138945
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adaptiveantibodycellularcholeraimmunityinnatememorymucosalsystemicvaccineVibrio cholerae

Identifiers

PMID34842841
PMCPMC8628923
OpenAlexW3208743108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.