Evidence map›Paper›PMID 34842772›Full record

ArticleNeurology international2021

Nicholas A Boehler, Samuel W Fung, Sara Hegazi, Arthur H Cheng, Hai-Ying Mary Cheng

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicholas A BoehlerDepartment of Biology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.
Samuel W FungDepartment of Biology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.ORCID 0000-0003-3230-2639
Sara HegaziDepartment of Biology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.
Arthur H ChengDepartment of Biology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.
Hai-Ying Mary ChengDepartment of Biology, University of Toronto Mississauga, Mississauga, ON L5L 1C6, Canada.ORCID 0000-0002-9292-7406
University of Toronto · CA

Funding

CIHR PJT-166046Natural Sciences and Engineering Research Council of Canada RGPIN-2016-05563
6 · The paper itself

Abstract

Mood disorders negatively impact the lives of hundreds of millions of individuals worldwide every year, yet the precise molecular mechanisms by which they manifest remain elusive. Circadian dysregulation is one avenue by which mood disorders are thought to arise. SOX2 is a transcription factor that is highly expressed in the murine suprachiasmatic nucleus (SCN), the circadian master clock, and has been recently found to be an important regulator of

Indexed as

anxietycircadian rhythmsdepressionmoodSox2suprachiasmatic nucleus

Identifiers

PMID34842772
PMCPMC8628992
OpenAlexW3210840772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.