Evidence map›Paper›PMID 34842768›Full record

ArticleNon-coding RNA2021

Between the Devil and the Deep Blue Sea: Non-Coding RNAs Associated with Transmissible Cancers in Tasmanian Devil, Domestic Dog and Bivalves.

Nicholas C Lister, Ashley M Milton, Benjamin J Hanrahan, Paul D Waters

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Non-coding RNA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas C ListerSchool of Biotechnology and Biomedical Sciences, Faculty of Science, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0002-6597-4784
Ashley M MiltonSchool of Biotechnology and Biomedical Sciences, Faculty of Science, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0002-2847-2777
Benjamin J HanrahanSchool of Biotechnology and Biomedical Sciences, Faculty of Science, UNSW Sydney, Sydney, NSW 2052, Australia.ORCID 0000-0001-9567-0071
Paul D WatersSchool of Biotechnology and Biomedical Sciences, Faculty of Science, UNSW Sydney, Sydney, NSW 2052, Australia.
UNSW Sydney · AU

Funding

Australian Research Council DP170101147Australian Research Council DP180100931Australian Research Council DP210103512
6 · The paper itself

Abstract

Currently there are nine known examples of transmissible cancers in nature. They have been observed in domestic dog, Tasmanian devil, and six bivalve species. These tumours can overcome host immune defences and spread to other members of the same species. Non-coding RNAs (ncRNAs) are known to play roles in tumorigenesis and immune system evasion. Despite their potential importance in transmissible cancers, there have been no studies on ncRNA function in this context to date. Here, we present possible applications of the CRISPR/Cas system to study the RNA biology of transmissible cancers. Specifically, we explore how ncRNAs may play a role in the immortality and immune evasion ability of these tumours.

Indexed as

bivalvecancerCRISPR/Casdomestic dogncRNAsTasmanian deviltransmissible

Identifiers

PMID34842768
PMCPMC8628904
OpenAlexW3214303984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.