Evidence map›Paper›PMID 34842707›Full record

ArticleInfectious disease reports2021

Prognostic Role of Anemia in COVID-19 Patients: A Meta-Analysis.

Marco Zuin, Gianluca Rigatelli, Laura Quadretti, Luisella Fogato, Giovanni Zuliani, Loris Roncon

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  10. Cardiovascular Disease Management in the Context of Global Crisis.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marco ZuinDepartment of Translational Medicine, Section of Internal and Cardio Respiratory Medicine, University of Ferrara, 44124 Ferrara, Italy.ORCID 0000-0002-4559-1292
Gianluca RigatelliDepartment of Cardiology, Rovigo General Hospital, 45100 Rovigo, Italy.
Laura QuadrettiDepartment of Medicine, Casa di Cura Porto Viro, 45014 Rovigo, Italy.
Luisella FogatoDepartment of General Surgery, Santa Maria degli Angeli Hospital, 06081 Adria, Italy.
Giovanni ZulianiDepartment of Translational Medicine, Section of Internal and Cardio Respiratory Medicine, University of Ferrara, 44124 Ferrara, Italy.
Loris RonconDepartment of Cardiology, Rovigo General Hospital, 45100 Rovigo, Italy.
Ospedale Santa Maria della Misericordia di Rovigo · ITUniversity of Ferrara · ITAzienda Ospedaliera Santa Maria Degli Angeli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe prevalence and prognostic implications of anemia in patients infected by the SARS-CoV-2 remains unclear. We performed a systematic review and meta-analysis to assess the prevalence and mortality risk in COVID-19 patients with anemia.

methodsPreferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed in abstracting data and assessing validity. We searched MEDLINE and Scopus to locate all the articles published up to 1 September 2021, reporting data on the adjusted OR (aOR) for mortality among COVID-19 patients with anemia. The pooled prevalence of anemia among COVID-19 patients was calculated using a random effects model and presenting the related 95% confidence interval (CI), while the mortality risk was estimated using the Mantel-Haenszel random effects models with odds ratio (aOR) and related 95% CI. Statistical heterogeneity was measured using the Higgins I

resultsFive studies, enrolling 9.623 COVID-19 patients [3.707 males (38.5%)], met the inclusion criteria and were included in the final analysis. The pooled prevalence of anemia was 25.6% of cases (95% CI: 8.3-56.5%), with high heterogeneity (I

conclusionsAnemia represents a major comorbidity in about 25% of COVID-19 patients and it is associated with about 70% higher risk of short-term mortality.

Indexed as

anemiaCOVID-19mortalityprevalence

Identifiers

PMID34842707
PMCPMC8628963
OpenAlexW3210302213

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.