Evidence map›Paper›PMID 34842690›Full record

ArticleGels (Basel, Switzerland)2021

Dynamics of a Gel-Based Artificial Tear Film with an Emphasis on Dry Disease Treatment Applications.

Hamza Mehdaoui, Hamid Ait Abderrahmane, Clement de Loubens, Faïçal Nait Bouda, Sofiane Hamani

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hamza MehdaouiLaboratoire de Mécanique, Matériaux et Energétique, Faculté de Technologie, Université de Bejaia, Bejaia 06000, Algeria.
Hamid Ait AbderrahmaneDepartment of Mechanical Engineering, Khalifa University, Abu Dhabi P.O. Box 127788, United Arab Emirates.ORCID 0000-0001-8467-0148
Clement de LoubensUniv. Grenoble Alpes, CNRS, Grenoble INP, LRP, 38000 Grenoble, France.ORCID 0000-0002-4988-9168
Faïçal Nait BoudaLaboratoire de Mécanique, Matériaux et Energétique, Faculté de Technologie, Université de Bejaia, Bejaia 06000, Algeria.
Sofiane HamaniLaboratoire de Recherche en Hydraulique Appliquée et Environnement, Faculté de Technologie, Université de Bejaia, Bejaia 06000, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper discusses the spreading of gel-based ophthalmic formulation on the cornea surface assumed to be flat. We show that gel-based formulations exhibit rheological behaviors that the Herschel-Bulkley model can describe. The continuity and momentum equations are solved numerically using the monofluid formulation and the volume-of-fluid (VOF) method. We investigated the influence of the rheological properties, namely the consistency, the yield stress, and the flow behavior index, on the spreading of a gel-based artificial tear over the cornea surface. We propose optimal values of these properties for efficient gel-based artificial tears.

Indexed as

dry eye diseasegel-based artificial tearsHerschel–Bulkley modeltear film breakupVOF method

Identifiers

PMID34842690
PMCPMC8628727

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.