Evidence map›Paper›PMID 34842664›Full record

ArticleGels (Basel, Switzerland)2021

Stable DNA Aptamer-Metal-Organic Framework as Horseradish Peroxidase Mimic for Ultra-Sensitive Detection of Carcinoembryonic Antigen in Serum.

Lingjun Sha, Mingcong Zhu, Fuqing Lin, Xiaomeng Yu, Langjian Dong, Licheng Wu, Rong Ding, Shuai Wu, Jingjing Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lingjun ShaCenter for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Mingcong ZhuSino-European School of Technology of Shanghai University, Shanghai University, Shanghai 200444, China.
Fuqing LinSchool of Basic Medical Sciences, Fudan University, Shanghai 200433, China.
Xiaomeng YuCenter for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Langjian DongCenter for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.
Licheng WuSino-European School of Technology of Shanghai University, Shanghai University, Shanghai 200444, China.
Rong DingSino-European School of Technology of Shanghai University, Shanghai University, Shanghai 200444, China.
Shuai WuState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, China.
Jingjing XuCenter for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, China.

Funding

National Natural Science Foundation of China 22001162National Natural Science Foundation of China 81772593Science and Technology Commission of Shanghai Municipality 20YF1414200
6 · The paper itself

Abstract

Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. For CEA detection, a novel type of metal-organic framework (MOF) was prepared by grafting CEA aptamer-incorporated DNA tetrahedral (TDN) nanostructures into PCN-222 (Fe)-based MOF (referred as CEA

Indexed as

carcinoembryonic antigencatalytic oxidationcolloid nanorodscolorimetric detectionDNA tetrahedron nanostructure

Identifiers

PMID34842664
PMCPMC8628696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.