Evidence map›Paper›PMID 34842602›Full record

ArticleInternational journal of neonatal screening2021

The Alberta Newborn Screening Approach for Sickle Cell Disease: The Advantages of Molecular Testing.

Janet R Zhou, Ross Ridsdale, Lauren MacNeil, Margaret Lilley, Stephanie Hoang, Susan Christian, Pamela Blumenschein, Vanessa Wolan, Aisha Bruce, Gurpreet Singh and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of neonatal screening, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Janet R ZhouNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
Ross RidsdaleNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
Lauren MacNeilNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.ORCID 0000-0003-3827-7147
Margaret LilleyNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
Stephanie HoangNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.ORCID 0000-0001-7147-1916
Susan ChristianNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.ORCID 0000-0001-5248-3049
Pamela BlumenscheinNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
Vanessa WolanNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
Aisha BruceDepartment of Pediatrics, University of Alberta, Edmonton, AB T6G 1C9, Canada.
Gurpreet SinghDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB T3B 6A8, Canada.
Nicola WrightDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB T3B 6A8, Canada.
Jillian S ParboosinghDepartment of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB T3B 6A8, Canada.
Ryan E LamontDepartment of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB T3B 6A8, Canada.
Iveta SosovaNewborn Metabolic Screening and Biochemical Genetics Laboratory, University of Alberta Hospital, Alberta Precision Laboratories, Edmonton, AB T6G 2B7, Canada.
University of Alberta · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell disease (SCD), a group of inherited red blood cell (RBC) disorders caused by pathogenic variants in the beta-globin gene (

Indexed as

newborn screeningsickle cell diseasesickle cell trait

Identifiers

PMID34842602
PMCPMC8628932
OpenAlexW3212309324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.