Evidence map›Paper›PMID 34842600›Full record

ArticleInternational journal of neonatal screening2021

Province-Wide Stool Color Card Screening for Biliary Atresia in Lower-Saxony: Experiences with Passive Distribution Strategies and Results.

Omid Madadi-Sanjani, Joachim F Kuebler, Marie Uecker, Eva-Doreen Pfister, Ulrich Baumann, Berit Kunze-Hullmann, Jochen Blaser, Thomas Buck, Claus Petersen

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of neonatal screening, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07139717 (Evaluation of the Effectiveness of Stool Color Card in the Early Detection of Biliary Atresia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07139717 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of the Effectiveness of Stool Color Card in the Early Detection of Biliary Atresia: A Prospective Study.

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled100ConditionsStool Color Card, Biliary Atresia
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Diseases of bile duct in children.World journal of gastroenterology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Omid Madadi-SanjaniDepartment of Pediatric Surgery, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-7239-8973
Joachim F KueblerDepartment of Pediatric Surgery, Hannover Medical School, 30625 Hannover, Germany.
Marie UeckerDepartment of Pediatric Surgery, Hannover Medical School, 30625 Hannover, Germany.
Eva-Doreen PfisterDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.
Ulrich BaumannDivision of Pediatric Gastroenterology and Hepatology, Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, 30625 Hannover, Germany.
Berit Kunze-HullmannLeberkrankes Kind e.V., National German Patient Organization for Diseases of the Liver in Children, 20038 Hamburg, Germany.
Jochen BlaserRepresentative Office of Lower Saxony, Techniker Krankenkasse (Health Insurance), 30159 Hannover, Germany.
Thomas BuckMedical Association of Lower Saxony, Representative Office of Hannover, 30625 Hannover, Germany.
Claus PetersenDepartment of Pediatric Surgery, Hannover Medical School, 30625 Hannover, Germany.
Medizinische Hochschule Hannover · DETechniker Krankenkasse (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStool color card (SCC) screenings for biliary atresia (BA) have shown to improve Kasai timing and outcome significantly. Both obligatory and non-obligatory screenings with passive distribution strategies have proven to be effective. Therefore, we have initiated a voluntary SCC program and aim to describe our experience.

methodsSince 2017 we supply all maternity wards in Lower-Saxony with SCC. Attending pediatricians and parents of BA infants were contacted via questionnaires and asked for their evaluation of the SCC screening.

results85.2% of attending pediatricians support the SCC screening, but only 78.1% considered the initiative useful. In their clinical routine, only 67% of visiting parents report to have received an SCC at the maternity hospital. In the group of parents of BA infants, only 54% (7/13) had received an SCC. Out of those seven parents, only one had referred their child to a children's hospital based on pathological SCC results. The lack of SCC education in the maternity hospitals was made responsible by parents. Within three years, only one infant with BA was identified through the SCC.

conclusionsOur voluntary SCC screening shows serious limitations with inacceptable distribution of SCCs and low acceptance of attending pediatricians. SCC programs in decentralized health care systems without educational campaigns, standardized diagnostic and treatment algorithms and the definition of reference centers are additional burdens for local health care providers without the promised benefit.

Indexed as

biliary atresiaKasai portoenterostomyscreening

Identifiers

PMID34842600
PMCPMC8629020
OpenAlexW3210166958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.