Evidence map›Paper›PMID 34842594›Full record

ReviewActa bio-medica : Atenei Parmensis2021

United airway disease.

Angela Klain, Cristiana Indolfi, Giulio Dinardo, Amelia Licari, Fabio Cardinale, Carlo Caffarelli, Sara Manti, Giampaolo Ricci, Giuseppe Pingitore, Mariangela Tosca and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  7. Article
  8. Review
  9. Article
  10. Biologics for eosinophilic otitis media: a retrospective case study in a multidisciplinary center.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Observational
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. ATP functions as a primary alarmin in allergen-induced type 2 immunity.American journal of physiology. Cell physiology · 2023
    Review
  18. Review
  19. [Risk factors for the development of airway hyperresponsiveness in patients with allergic rhinitis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Angela KlainDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. klainangela95@gmail.com.
Cristiana IndolfiDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. cristianaind@hotmail.com.
Giulio DinardoDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. dinardogiulio@gmail.com.
Amelia LicariPediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy. a.licari@smatteo.pv.it.
Fabio CardinaleDepartment of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy. fabiocardinale@libero.it.
Carlo CaffarelliPediatric Clinic, Department of Medicine and Surgery, University of Parma, Parma, Italy. carlo.caffarelli@unipr.it.
Sara Manti6Department of Clinical and Experimental Medicine, Pediatric Respiratory Unit, San Marco Hospital, University of Catania, Catania, Italy; . saramanti@hotmail.it.
Giampaolo RicciDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, Italy. giampaolo.ricci@unibo.it.
Giuseppe PingitorePediatrician and Allergist, Rome, Italy. giuseppe.pingitore@gmail.com.
Mariangela ToscaAllergy Centre, IRCCS G. Gaslini Pediatric Hospital, Genova, Italy.. mariangelatosca@gaslini.org.
Fabio DecimoDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. fabio.decimo@unicampania.it.
Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. michele.miraglia@unicampania.it.
University of Campania "Luigi Vanvitelli" · ITIstituto Giannina Gaslini · ITOspedale Pediatrico Giovanni XXIII · ITOspedale San Giuseppe · ITUniversity of Bologna · ITUniversity of Catania · ITUniversity of Parma · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nose and lungs are considered as anatomic and functional unit, as they share morphological, pathophysiological and immunological basis. Allergic rhinitis and asthma often coexist in the same individual, and the treatment of one also improves the symptoms of the other (one airway, one disease). The aim of this review is to discuss the interaction between upper and lower airways, based on recent scientific evidence and, critically, analyze the important implications the new findings have for the future therapy and prevention of these common diseases.

Indexed as

AsthmaRespiration DisordersRhinitis, AllergicHumansLung

Identifiers

PMID34842594
PMCPMC9431894
OpenAlexW3217168257

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.