Evidence map›Paper›PMID 34842589›Full record

ReviewActa bio-medica : Atenei Parmensis2021

Biologic drugs in chronic spontaneous urticaria.

Amelia Licari, Sara Manti, Salvatore Leonardi, Domenico Minasi, Carlo Caffarelli, Fabio Cardinale, Michele Miraglia Del Giudice, Mauro Calvani, Giorgio Ciprandi, Gian Luigi Marseglia

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 1 country.

Amelia Licari1Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. amelia.licari@unipv.it.
Sara Manti1UOC Broncopneumologia Pediatrica e Fibrosi Cistica, AOUP "Vittorio-Emanuele", San Marco Hospital, Università di Catania, Catania, Italy. saramanti@hotmail.it.
Salvatore Leonardi3Department of Clinical and Experimental Medicine, Pediatric Respiratory Unit, San Marco Hospital, University of Catania, Catania, Italy. leonardi@unict.it.
Domenico MinasiPediatric Unit Great Metropolitan Hospital Reggio Calabria, Reggio Calabria, Italy. domenico.minasi@tiscali.it.
Carlo CaffarelliPediatric Clinic, Department of Medicine and Surgery, Unversity of Parma, Parma, Italy. carlo.caffarelli@unipr.it.
Fabio CardinaleDepartment of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy. fabio.cardinale@libero.it.
Michele Miraglia Del GiudiceDepartment of Woman, Child and Specialized Surgery, University of Campania "Luigi Vanvitelli. Michele.MIRAGLIADELGIUDICE@unicampania.it.
Mauro CalvaniUOC di Pediatria. Azienda ospedaliera S. Camillo Forlanini, Rome, Italy. maurocalvani58@gmail.com.
Giorgio CiprandiAllergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy. giocip@me.com.
Gian Luigi MarsegliaPediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. gl.marseglia@smatteo.pv.it.
University of Pavia · ITAzienda Ospedaliera San Camillo-Forlanini · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITCasa di Cura Villa Garda · ITOspedale Pediatrico Giovanni XXIII · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Catania · ITUniversity of Parma · ITUniversity of Reggio Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic spontaneous urticaria (CSU) is a condition defined by the presence of recurrent urticaria, angioedema, or both, which persist for more than six weeks in duration and occurs in the absence of an identifiable trigger. Both children and adults can develop CSU, although it is more common in adults and in women than in men, with a peak occurrence in the third to fifth decades of life. It imposes a significant burden on patients, families and healthcare systems. The goal of therapy in patients with CSU is to achieve a level of symptom control and improvement in quality of life that is acceptable to the patient, while minimizing therapy-related side effects. The recent introduction of biologic drugs has changed the management of the disease. This work aims to provide a narrative review of the current state of biological therapy and the promising drugs under development for CSU.

Indexed as

Biological ProductsChronic UrticariaUrticariaAdultChildChronic DiseaseFemaleHumansMaleQuality of LifeBiological Products

Identifiers

PMID34842589
PMCPMC9431883
OpenAlexW3216300375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.