Evidence map›Paper›PMID 34842587›Full record

ArticleActa bio-medica : Atenei Parmensis2021

Component resolved diagnosis and risk assessment in food allergy.

Alberto Martelli, Mauro Calvani, Thomas Foiadelli, Mariangela Tosca, Giuseppe Pingitore, Amelia Licari, Alessia Marseglia, Giorgio Ciprandi, Carlo Caffarelli

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alberto MartelliUniversity of Pavia, Pavia, Italy. albmartelli@tiscali.it.
Mauro CalvaniUOC di Pediatria. Azienda Ospedaliera S. Camillo Forlanini, Rome, Italy. maurocalvani58@gmail.com.
Thomas FoiadelliPediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy; Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. albmartelli@tiscali.it.
Mariangela ToscaAllergy Centre, IRCCS G. Gaslini Pediatric Hospital, Genova, Italy. mariangelatosca@gaslini.org.
Giuseppe PingitorePediatrician and Allergist, Rome, Italy. giuseppe.pingitore@gmail.com.
Amelia LicariPediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy; Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. a.licari@smatteo.pv.it.
Alessia MarsegliaPediatric Unit, Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, University of Pavia, Pavia, Italy; Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. albmartelli@tiscali.it.
Giorgio CiprandiAllergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy. gio.cip@libero.it.
Carlo CaffarelliPediatric Clinic, Department of Medicine and Surgery, Unversity of Parma, Parma, Italy. carlo.caffarelli@unipr.it.
Casa di Cura Columbus · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergy testing should only be performed in the context of the clinical history as history provides the cornerstone of diagnosis. In food allergy, some allergy tests often give rise to false positive results and thus can lead to unnecessary avoidance or delay on foods introduction. The use of Component Resolved Diagnosis in combination with conventional sensitization testing improves analytical and diagnostic performance and can lead to the reduction of diagnostic oral food challenges. Component Resolved Diagnosis can be helpful in identifying some risks for the allergic child. Molecular diagnosis can help also in predicting the development of the allergy march, in severe reactions (lipid transfer protein, seed storage proteins, etc.) in food allergy and for potential clinical cross-reactivity.

Indexed as

Food HypersensitivityImmunoglobulin EAllergensChildHumansRisk AssessmentSkin TestsAllergensImmunoglobulin E

Identifiers

PMID34842587
PMCPMC9431885
OpenAlexW3214954382

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.