ArticleJournal of medical Internet research2021
Patients' Perceptions Toward Human-Artificial Intelligence Interaction in Health Care: Experimental Study.
Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 3 syntheses or guidelines pooled it, 217 citations in OpenAlex.
- Barriers and Facilitators to Patient Acceptance of Artificial Intelligence in Health Care: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Patient Concerns Regarding Artificial Intelligence Applications in Health Care: Systematic Review and Meta-Synthesis Based on Social Ecological Theory.Journal of medical Internet research · 2026Pooled it
- Opportunities and challenges with artificial intelligence in allergy and immunology: a bibliometric study.Frontiers in medicine · 2025Pooled it
- Patient trust in the use of machine learning-based clinical decision support systems in psychiatric services: A randomized survey experiment.European psychiatry : the journal of the Association of European Psychiatrists · 2024Trial
- Effects of Type and Timing of Clinician-Facing AI Support on Patient Trust in Medical Consultations: 2 Vignette Experiments.Journal of medical Internet research · 2026Article
- The Challenges of AI Applications in Health Care: Qualitative Study.Journal of medical Internet research · 2026Article
- Patients' experiences and attitudes toward the use of real-time artificial intelligence-assisted colonoscopy.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Research on the Improvement Path of Human-AI Collaborative Consultation Effectiveness From the Perspective of Information Ecology: Configurational Analysis.JMIR medical informatics · 2026Article
- The ethics of listening walls: patient autonomy and consent in the age of ambient clinical AI.NPJ digital medicine · 2026Article
- Feasibility and user evaluation of HopeBot: An LLM-powered conversational chatbot for depression screening.PLOS digital health · 2026Article
- Human-AI Interaction in Kidney Transplant Decision Support Systems: Qualitative Study of Patient and Support Person Expectations.Journal of medical Internet research · 2026Article
- Use of AI scribes in UK primary care: a survey of general practitioners.NPJ digital medicine · 2026Article
- Why care resists coding: the moral limits of medical AI.BMC medical ethics · 2026Article
- Public Perceptions of AI in Medicine and Implications for Future Medical Education: Cross-Sectional Survey.JMIR formative research · 2026Article
- Patient perspectives about deployment of artificial intelligence decision support tools in a safety-net healthcare system.JAMIA open · 2026Article
- Achilles tendon ruptures: still very much in the limelight, and still controversial. Not all research is as glittering as it may look.Journal of orthopaedic surgery and research · 2026Article
- Three Shifts That Will Redefine Health Systems.Health care science · 2026Article
- Patient Perspectives on AI-Powered Medical Robots in Breast and Prostate Cancer Care: Qualitative Study.JMIR cancer · 2026Article
- Ethical Responsibility in Medical AI: A Semi-Systematic Thematic Review and Multilevel Governance Model.Healthcare (Basel, Switzerland) · 2026Review
- AI outperforms humans in establishing interpersonal closeness in emotionally engaging interactions, but only when labelled as human.Communications psychology · 2026Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is believed that artificial intelligence (AI) will be an integral part of health care services in the near future and will be incorporated into several aspects of clinical care such as prognosis, diagnostics, and care planning. Thus, many technology companies have invested in producing AI clinical applications. Patients are one of the most important beneficiaries who potentially interact with these technologies and applications; thus, patients' perceptions may affect the widespread use of clinical AI. Patients should be ensured that AI clinical applications will not harm them, and that they will instead benefit from using AI technology for health care purposes. Although human-AI interaction can enhance health care outcomes, possible dimensions of concerns and risks should be addressed before its integration with routine clinical care.
objectiveThe main objective of this study was to examine how potential users (patients) perceive the benefits, risks, and use of AI clinical applications for their health care purposes and how their perceptions may be different if faced with three health care service encounter scenarios.
methodsWe designed a 2×3 experiment that crossed a type of health condition (ie, acute or chronic) with three different types of clinical encounters between patients and physicians (ie, AI clinical applications as substituting technology, AI clinical applications as augmenting technology, and no AI as a traditional in-person visit). We used an online survey to collect data from 634 individuals in the United States.
resultsThe interactions between the types of health care service encounters and health conditions significantly influenced individuals' perceptions of privacy concerns, trust issues, communication barriers, concerns about transparency in regulatory standards, liability risks, benefits, and intention to use across the six scenarios. We found no significant differences among scenarios regarding perceptions of performance risk and social biases.
conclusionsThe results imply that incompatibility with instrumental, technical, ethical, or regulatory values can be a reason for rejecting AI applications in health care. Thus, there are still various risks associated with implementing AI applications in diagnostics and treatment recommendations for patients with both acute and chronic illnesses. The concerns are also evident if the AI applications are used as a recommendation system under physician experience, wisdom, and control. Prior to the widespread rollout of AI, more studies are needed to identify the challenges that may raise concerns for implementing and using AI applications. This study could provide researchers and managers with critical insights into the determinants of individuals' intention to use AI clinical applications. Regulatory agencies should establish normative standards and evaluation guidelines for implementing AI in health care in cooperation with health care institutions. Regular audits and ongoing monitoring and reporting systems can be used to continuously evaluate the safety, quality, transparency, and ethical factors of AI clinical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.