Evidence map›Paper›PMID 34842509›Full record

ArticleEmerging microbes & infections2022

A CRISPR/Cas12a-based DNAzyme visualization system for rapid, non-electrically dependent detection of

Dongshu Wang, Gang Chen, Yufei Lyu, Erling Feng, Li Zhu, Chao Pan, Weicai Zhang, Xiankai Liu, Hengliang Wang

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
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  12. Review
  13. Rapid Identification ofMicroorganisms · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Recent Advances in CRISPR-Cas Technologies for Synthetic Biology.Journal of microbiology (Seoul, Korea) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dongshu WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Gang ChenState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Yufei LyuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Erling FengState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Li ZhuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Chao PanState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Weicai ZhangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Xiankai LiuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Hengliang WangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Biotechnology, Beijing, People's Republic of China.
Czech Academy of Sciences, Institute of Biotechnology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As next-generation pathogen detection methods, CRISPR-Cas-based detection methods can perform single-nucleotide polymorphism (SNP) level detection with high sensitivity and good specificity. They do not require any particular equipment, which opens up new possibilities for the accurate detection and identification of

Indexed as

AnthraxAntisense Elements (Genetics)Bacillus anthracisBacterial ProteinsCRISPR-Associated ProteinsCRISPR-Cas SystemsDNA, BacterialDNA, CatalyticEndodeoxyribonucleasesG-QuadruplexesPlasmidsAntisense Elements (Genetics)Bacterial ProteinsCas12a proteinCRISPR-Associated ProteinsDNA, BacterialDNA, CatalyticEndodeoxyribonucleasesBacillus anthraciscolour changeCRISPR-Cas12adetectionDNAzyme

Identifiers

PMID34842509
PMCPMC8812752
OpenAlexW3215269732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.