ArticleeLife2021
Effects of arousal and movement on secondary somatosensory and visual thalamus.
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- The role of transthalamic pathways in perception.Communications biology · 2026Review
- Presynaptic control of top-down signaling in neocortical layer 1.bioRxiv : the preprint server for biology · 2026Article
- Layer 5 myelination gates corticothalamic coincidence detection.Nature communications · 2025Article
- Thalamus enables active dendritic coupling of inputs arriving at different cortical layers.Nature communications · 2025Article
- Role of posterior medial thalamus in the modulation of striatal circuitry and choice behavior.eLife · 2025Article
- Article
- Active and passive touch are differentially represented in the mouse somatosensory thalamus.PLoS biology · 2025Article
- Behavioral adaptations after unilateral whisker denervation.Behavioural brain research · 2025Article
- Higher-order thalamic input to cortex selectively conveys state information.Cell reports · 2025Article
- Article
- Article
- Article
- Attentional modulation of secondary somatosensory and visual thalamus of mice.bioRxiv : the preprint server for biology · 2024Article
- Stability of cross-sensory input to primary somatosensory cortex across experience.bioRxiv : the preprint server for biology · 2024Article
- Co-coding of head and whisker movements by both VPM and POm thalamic neurons.Nature communications · 2024Article
- Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scales.PLoS biology · 2024Article
- Interareal Synaptic Inputs Underlying Whisking-Related Activity in the Primary Somatosensory Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Review
- Transthalamic input to higher-order cortex selectively conveys state information.bioRxiv : the preprint server for biology · 2023Article
- Monosynaptic trans-collicular pathways link mouse whisker circuits to integrate somatosensory and motor cortical signals.PLoS biology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Neocortical sensory areas have associated primary and secondary thalamic nuclei. While primary nuclei transmit sensory information to cortex, secondary nuclei remain poorly understood. We recorded juxtasomally from secondary somatosensory (POm) and visual (LP) nuclei of awake mice while tracking whisking and pupil size. POm activity correlated with whisking, but not precise whisker kinematics. This coarse movement modulation persisted after facial paralysis and thus was not due to sensory reafference. This phenomenon also continued during optogenetic silencing of somatosensory and motor cortex and after lesion of superior colliculus, ruling out a motor efference copy mechanism. Whisking and pupil dilation were strongly correlated, possibly reflecting arousal. Indeed LP, which is not part of the whisker system, tracked whisking equally well, further indicating that POm activity does not encode whisker movement per se. The semblance of movement-related activity is likely instead a global effect of arousal on both nuclei. We conclude that secondary thalamus monitors behavioral state, rather than movement, and may exist to alter cortical activity accordingly.
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