Evidence map›Paper›PMID 34841907›Full record

Observational studyClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Anticoagulation Duration After First Venous Thromboembolism: Real-Life Data From the International, Observational WHITE Study.

Gualtiero Palareti, Angelo A Bignamini, Michela Cini, Young-Jun Li, Tomasz Urbanek, Juraj Madaric, Kamel Bouslama, German Y Sokurenko, Giuseppe M Andreozzi, Jiří Matuška and 2 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 7 countries.

Gualtiero PalaretiArianna Anticoagulazione Foundation, Bologna, Italy.ORCID https://orcid.org/0000-0002-4327-9561
Angelo A BignaminiSchool of Specialization in Hospital Pharmacy, 9304University of Milan, Milan, Italy.
Michela CiniArianna Anticoagulazione Foundation, Bologna, Italy.ORCID https://orcid.org/0000-0001-9681-6159
Young-Jun LiPeking Union Medical College, 12501Chinese Academy of Medical Sciences, Beijing, China.
Tomasz Urbanek49613Medical University of Silesia, Katowice, Poland.
Juraj MadaricClinic of Angiology, Comenius University and National Institute of Cardiovascular Diseases, Bratislava, Slovakia.
Kamel BouslamaFaculty of Medicine of Tunis, 59074University of Tunis El Manar, Tunis, Tunisia.
German Y SokurenkoNorth-West Mechnikov State Medical University, St. Petersburg, Russia.
Giuseppe M AndreozziAngiology Unit, 9308University of Padua, Padova, Italy.
Jiří MatuškaClinical Trial Centre, Hodonin, Czechia.
Armando Mansilha26706University of Porto, Porto, Portugal.
Victor BarinovClinical Hospital N. 1 "Volynskaya", Moscow, Russia.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNMedical University of Silesia · PLNational Institute of Cardiovascular Diseases · SKNorth-Western State Medical University named after I.I. Mechnikov · RUTunis University · TNUniversidade do Porto · PTUniversity of Milan · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInternational guidelines recommend at least three months anticoagulation in all patients after acute venous thromboembolism (VTE) and suggest those with unprovoked events be considered for indefinite anticoagulation if the risk of recurrence is high and the risk of bleeding during treatment non-high. Other authors have recently argued against using a dichotomy unprovoked/provoked events to decide on anticoagulation duration and suggest instead using overall risk factors present in each patient as the basis for deciding.

aimThis sub-analysis of the WHITE study aimed at assessing the reasons for the treatment decisions taken by doctors in different countries.

results1240 patients were recruited in 7 countries (China, Czechia, Poland, Portugal, Russia, Slovakia, and Tunisia). Anticoagulation was extended in 51.7% and 49.3% of patients with unprovoked or provoked events (n.s.); stopped in 15.4% versus 28.9% (

conclusionOn average, attending physicians estimated the risk of recurrence in real life conditions, and the consequent therapeutic decision, using all the information available, not limiting to the location or nature of the index event.

Indexed as

AnticoagulantsBlood CoagulationChinaHumansIncidenceRisk FactorsVenous ThromboembolismAnticoagulantsanticoagulantsanticoagulationantithromboticsaspirinsulodexidevenous thromboembolism

Identifiers

PMID34841907
PMCPMC8674483
OpenAlexW3216394196

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.