Evidence map›Paper›PMID 34841905›Full record

SynthesisJournal of cutaneous medicine and surgery

Eruptive Seborrheic Keratoses Are Associated With a Co-Occurring Malignancy in the Majority of Reported Cases: A Systematic Review.

Sara Mirali, Asfandyar Mufti, Rafael Paolo Lansang, Muskaan Sachdeva, Jensen Yeung

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Journal of cutaneous medicine and surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Causality of inflammatory bowel disease and seborrheic keratosis: A bidirectional two-sample Mendelian randomization study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sara Mirali12366 Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0001-6233-9067
Asfandyar Mufti7938 Department of Dermatology, University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-3514-9513
Rafael Paolo Lansang62703 Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada.
Muskaan Sachdeva12366 Faculty of Medicine, University of Toronto, Toronto, ON, Canada.ORCID https://orcid.org/0000-0002-2252-5663
Jensen Yeung7938 Department of Dermatology, University of Toronto, Toronto, ON, Canada.
University of Toronto · CAMcMaster University · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEruptive seborrheic keratoses (ESK) is a benign skin condition that has been associated with malignant and nonmalignant diseases. We conducted a systematic review of reported cases of ESK to identify and summarize associated comorbidities.

methodsMEDLINE and Embase were searched from database inception (1946) to July 31, 2020 for original articles describing ESK with or without a co-occurring condition. Subject demographics, as well as details of ESK and associated diagnoses were extracted from 76 articles (70 case reports, 3 case series, 3 case control studies) representing 92 patients.

resultsIn total, 76.1% (

conclusionAlthough the role of ESK as a paraneoplastic cutaneous marker is debated, healthcare providers should consider screening for underlying malignancy in patients presenting with ESK. Larger studies are needed to confirm its role as a marker for disease.

Indexed as

ComorbidityGastrointestinal NeoplasmsHumansKeratosis, SeborrheicLymphoma, T-Cell, CutaneousPrecancerous ConditionsSkin NeoplasmsadenocarcinomacancerEruptive seborrheic keratosesESKLeser-Trelatlichenoid keratosessystematic review

Identifiers

PMID34841905
PMCPMC8750131
OpenAlexW3215050101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.