Evidence map›Paper›PMID 34841729›Full record

ReviewClinical and translational allergy2021

Effectiveness of mobile health interventions to improve nasal corticosteroid adherence in allergic rhinitis: A systematic review.

Mats Stage Baxter, Holly Tibble, Andrew Bush, Aziz Sheikh, Jürgen Schwarze

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and translational allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Digital health tools in the management of allergic rhinitis: a systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Pooled it
  2. Review
  3. Review
  4. An Overview of Adherence-What It Is and Why It Is Important.The journal of allergy and clinical immunology. In practice · 2024
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mats Stage BaxterUsher Institute, The University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0001-6865-4113
Holly TibbleUsher Institute, The University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0001-7169-4087
Andrew BushAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0001-6756-9822
Aziz SheikhUsher Institute, The University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0001-7022-3056
Jürgen SchwarzeAsthma UK Centre for Applied Research, Usher Institute, The University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-6899-748X
Institute of Occupational Medicine · GBRoyal Brompton Hospital · GB

Funding

Chief Scientist Office Asthma UK Centre for Applied Research/20/01Chief Scientist Office AUKCAR/20/01
6 · The paper itself

Abstract

backgroundMobile health interventions (MHI) offer the potential to help improve nasal corticosteroid (NCS) adherence in allergic rhinitis (AR). The aim of this systematic review was to summarise the current evidence on the effectiveness of MHI for improving NCS adherence in AR.

methodsWe systematically searched MEDLINE, Embase and the Cochrane Central register of Controlled Trials (CENTRAL) for randomised controlled trials filtered for publication dates between 2010 and 2021. We evaluated the effects of MHI aiming to improve NCS adherence on self-management outcomes in AR and comorbid conditions. Two reviewers independently screened potential studies, extracted study characteristics and outcomes from eligible papers and assessed risk of bias using the Cochrane Risk of Bias tool 2.0. High heterogeneity precluded meta-analysis. Data were descriptively and narratively synthesised.

resultsOur searches identified 776 individual studies of which 4 met the inclusion criteria. These studies were heterogeneous with respect to participant, intervention and outcome characteristics. We considered all outcome-specific overall risk of bias assessments to be of high risk of bias except for two studies examining NCS adherence which received 'some concern' grades. The three studies which reported on NCS adherence found that MHI were associated with improvement in NCS adherence. Significant MHI-associated improvement in symptoms or disease-specific quality of life was found in one study each, whilst no study reported significant differences in nasal patency.

conclusionsWhilst MHI showed potential to improve NCS adherence, their effect on clinical outcomes varied. Furthermore, robust studies with longer intervention durations are needed to adequately assess effects of MHI and their individual features on NCS adherence and clinical outcomes.

Indexed as

allergic rhinitisAllergische Rhinitishay feverHeuschnupfenmedication adherenceMedikamentenadhärenzmHealth interventionsMobile Gesundheitsinterventionnasal corticosteroidsNasale Kortikosteroide

Identifiers

PMID34841729
PMCPMC9815425
OpenAlexW3213529097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.