Evidence map›Paper›PMID 34841725›Full record

ArticleClinical and translational medicine2021

Synthetic molecular sensors based on CRISPR-Cas9 redirect anticancer signal flows to treat retinoblastomas.

Lulu Xiao, Jun Li, Yiyu Sheng, Ye Wang, Xiaoyan Dou

Open access · goldAbstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lulu XiaoDepartment of Ophthalmology, Shenzhen Hospital of Southern Medical University, Southern Medical University, Shenzhen, China.ORCID 0000-0003-2546-4197
Jun LiThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Yiyu ShengThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Ye WangDepartment of Ophthalmology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Xiaoyan DouDepartment of Ophthalmology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Shenzhen Second People's Hospital · CNSun Yat-sen University · CNSouthern Medical University Shenzhen Hospital · CN

Funding

Clinical Research Project of Shenzhen Second People's Hospital 20193357009Shenzhen Science and Technology R&D Fund Project JCYJ20150330102720161
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clustered Regularly Interspaced Short Palindromic RepeatsGene EditingHumansRetinoblastomaSignal Transduction

Identifiers

PMID34841725
PMCPMC8574887
OpenAlexW3211411934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.