Evidence map›Paper›PMID 34841704›Full record

ArticleClinical and translational medicine2021

Berberine suppresses advanced glycation end products-associated diabetic retinopathy in hyperglycemic mice.

Ning Wang, Leilei Wang, Cheng Zhang, Hor-Yue Tan, Yinjian Zhang, Yibin Feng

Open access · goldAbstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Recent Advances in Nanozymes Toward Diabetic Foot Ulcers.International journal of nanomedicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ning WangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Leilei WangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Cheng ZhangSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Hor-Yue TanSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.
Yinjian ZhangDepartment of Ophthalmology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yibin FengSchool of Chinese Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China.ORCID 0000-0002-0241-670X
Chinese University of Hong Kong · HKHong Kong Baptist University · HKShanghai University of Traditional Chinese Medicine · CN

Funding

Chinese Medicine Studio of Zou Jusheng 09DZ1973900Gaia Family Trust of New Zealand 200007008Health and Medical Research Fund 15162961Health and Medical Research Fund 16172751Health and Medical Research Fund 17181101Inheritance and Study of Fan Ophthalmology of Traditional Chinese Medicine ZY3-CCCX-1-2004Research Grant Council, HKSAR 17121419Research Grant Council, HKSAR RGC GRF 17152116Wong's donation 200006276
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBerberineDiabetic RetinopathyDisease Models, AnimalGlycation End Products, AdvancedHyperglycemiaMiceBerberineGlycation End Products, Advanced

Identifiers

PMID34841704
PMCPMC8567055
OpenAlexW3211609380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.