Evidence map›Paper›PMID 34841476›Full record

ArticleJournal of cell communication and signaling2022

CD47 interactions with exportin-1 limit the targeting of m

Sukhbir Kaur, Alejandra Cavazos Saldana, Abdel G Elkahloun, Jennifer D Petersen, Anush Arakelyan, Satya P Singh, Lisa M Jenkins, Bethany Kuo, Bianca Reginauld, David G Jordan and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell communication and signaling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  8. International journal of molecular sciences · 2024
    Article
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  20. CD63Biomedicines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Sukhbir KaurLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA.ORCID http://orcid.org/0000-0003-0513-6225
Alejandra Cavazos SaldanaLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA.
Abdel G ElkahlounCancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA.
Jennifer D PetersenSection On Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA.
Anush ArakelyanSection On Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA.
Satya P SinghInflammation Biology Section, Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, USA.
Lisa M JenkinsLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA.
Bethany KuoLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA.
Bianca ReginauldLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA.
David G JordanLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA.
Andy D TranConfocal Microscopy Core Facility, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, USA.
Weiwei WuCancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, USA.
Joshua ZimmerbergSection On Integrative Biophysics, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA.
Leonid MargolisSection On Intercellular Interactions, Division of Basic and Translational Biophysics, Eunice Kennedy-Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA.
David D RobertsLaboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10 Room 2S235, 10 Center Dr, Bethesda, MD, 20892-1500, USA. droberts@mail.nih.gov.ORCID http://orcid.org/0000-0002-2481-2981
National Institutes of Health · US

Funding

Mechanisms and Intracellular Components in Exocytosis, Membrane Assembly and Repair, and Parasite ReplicationZIAHD001415 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ZIMMERBERG, JOSHUA · 2009 to 2025
$26.0M
Cellular Interactions with ThrombospondinZIASC009172 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI ROBERTS, DAVID D · 2009 to 2024
$17.9M
Viral transmission and pathogenesis in human tissuesZIAHD008968 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MARGOLIS, LEONID B. · 2018 to 2023
$12.2M
CPTR - Mass Spectrometry UnitZICBC011430 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JENKINS, LISA · 2012 to 2025
$9.4M
NHGRI/DIR Microarray CoreZICHG200365 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI ELKAHLOUN, ABDEL · 2011 to 2025
$9.0M
Roles of Glycoconjugates and Redox Signaling in Tumor BiologyZIASC009174 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI ROBERTS, DAVID D · 2009 to 2024
$4.9M
EXOCYTOTIC MEMBRANE FUSIONZ01HD001415 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ZIMMERBERG, JOSHUA · 1991 to 2008
$1.9M
CELLULAR INTERACTIONS WITH THROMBOSPONDINZ01SC009172 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI ROBERTS, DAVID D · 1996 to 2008
$1.7M
Intramural NIH HHS Z01 HD001415Intramural NIH HHS Z01 SC009172Intramural NIH HHS ZIA HD001415Intramural NIH HHS ZIA HD008968Intramural NIH HHS ZIA SC009172Intramural NIH HHS ZIC HG200365NCI NIH HHS ZIA SC009172NHGRI NIH HHS ZIC HG200365
6 · The paper itself

Abstract

CD47 is a marker of self and a signaling receptor for thrombospondin-1 that is also a component of extracellular vesicles (EVs) released by various cell types. Previous studies identified CD47-dependent functional effects of T cell EVs on target cells, mediated by delivery of their RNA contents, and enrichment of specific subsets of coding and noncoding RNAs in CD47

Indexed as

CD47Exportin-1Extracellular vesiclesMicro-RNARNA traffickingUbiquilin-1

Identifiers

PMID34841476
PMCPMC9411329
OpenAlexW3217545016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.