Evidence map›Paper›PMID 34841464›Full record

ArticleApplied microbiology and biotechnology2021

Identification and a phased pH control strategy of diosgenin bio-synthesized by an endogenous Bacillus licheniformis Syt1 derived from Dioscorea zingiberensis C. H. Wright.

Zhongqiu Hu, Chunli Wang, Lintao Pan, Shiyao Han, Miao Jin, Yongsheng Xiang, Lifei Zheng, Zhonghong Li, Rang Cao, Baofu Qin

Abstract read
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In one paragraph

Article in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zhongqiu HuCollege of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.ORCID http://orcid.org/0000-0003-0112-3304
Chunli WangYangLing Demonstration Zone Hospital, Yangling, Shaanxi, 712100, People's Republic of China.
Lintao PanCollege of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Shiyao HanCollege of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Miao JinCollege of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Yongsheng XiangCollege of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Lifei ZhengCollege of Science, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Zhonghong LiCollege of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Rang CaoCollege of Grassland Agriculture, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China.
Baofu QinCollege of Life Sciences, Northwest A&F University, Yangling, Shaanxi, 712100, People's Republic of China. baofu_qin@aliyun.com.ORCID http://orcid.org/0000-0002-9284-7713
Northwest A&F University · CNGuangzhou Development Zone Hospital · CNNorth West Agriculture and Forestry University · CN

Funding

shaanxi provincial science and technology department 2015KTCQ03-05shaanxi provincial science and technology department 2021SF-387
6 · The paper itself

Abstract

Diosgenin is widely used as one precursor of steroidal drugs in pharmaceutical industry. Currently, there is no choice but to traditionally extract diosgenin from Dioscorea zingiberensis C. H. Wright (DZW) or other plants. In this work, an environmentally friendly approach, in which diosgenin can be bio-synthesized by the endophytic bacterium Bacillus licheniformis Syt1 isolated from DZW, is proposed. Diosgenin produced by the strain was identified by high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and Fourier transform infrared spectroscopy (FTIR). The thermal gravimetric analysis (TGA) showed that the melting point of the diosgenin product was 204 °C. The optical rotation measurement exhibited that the optical rotation was α

Indexed as

Bacillus licheniformisDioscoreaDiosgeninSaponinsHydrogen-Ion ConcentrationDiosgeninSaponinsBatch fermentationDiosgeninEndophytic Bacillus licheniformis Syt1Isolation and identificationpH control strategy

Identifiers

PMID34841464
OpenAlexW3216385848

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.