Evidence map›Paper›PMID 34841220›Full record

ArticleACS applied bio materials2020

Targeted Imaging of CD206 Expressing Tumor-Associated M2-like Macrophages Using Mannose-Conjugated Antibiofouling Magnetic Iron Oxide Nanoparticles.

Yuancheng Li, Hui Wu, Bing Ji, Weiping Qian, Siyuan Xia, Liya Wang, Yaolin Xu, Jing Chen, Lily Yang, Hui Mao

Open access · greenAbstract read
In one paragraph

Article in ACS applied bio materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 60 citations in OpenAlex.

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  14. Development of molecular sensors based on fluorescent proteins for polarized macrophages identification.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
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  19. Article
  20. New Weapons to Fight againstAntibiotics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Yuancheng LiDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States.
Hui WuDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States.
Bing JiDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States.
Weiping QianDepartment of Surgery, Emory University, Atlanta, Georgia 30329, United States.
Siyuan XiaDepartment of Hematology and Medical Oncology, Emory University, Atlanta, Georgia 30329, United States.
Liya WangDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States; Department of Radiology, The People's Hospital of Longhua, Shenzhen, Guangdong 518109, China.
Yaolin XuDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States.
Jing ChenDepartment of Hematology and Medical Oncology, Emory University, Atlanta, Georgia 30329, United States.
Lily YangDepartment of Surgery, Emory University, Atlanta, Georgia 30329, United States.ORCID 0000-0003-2959-0094
Hui MaoDepartment of Radiology and Imaging Sciences, Emory University, Atlanta, Georgia 30329, United States.ORCID 0000-0002-0147-6022
Emory University · US

Funding

Stroma Breaking Theranostic Nanoparticle for Targeted Pancreatic Cancer TherapyU01CA198913 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2015 to 2019
$3.0M
Targeted therapy of peritoneal carcinomatosis using theranostic nanoparticlesR01CA202846 · NCI · EMORY UNIVERSITY · PI MAO, HUI, WANG, YONGQIANG ANDREW · 2016 to 2020
$2.4M
Theranostic Nano particles for Targeted Treatment of Pancreatic CancerU01CA151810 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2010 to 2014
$2.2M
MRI Capable Receptor Targeted Drug Delivery for Pancreatic CancerR01CA154846 · NCI · EMORY UNIVERSITY · PI MAO, HUI, YANG, LILY · 2011 to 2015
$2.1M
NCI NIH HHS R01 CA154846NCI NIH HHS R01 CA202846NCI NIH HHS U01 CA151810NCI NIH HHS U01 CA198913
6 · The paper itself

Abstract

Although tumor-associated macrophages (TAMs) have been shown to promote cancer progression, their roles in tumor development and resistance to therapy remain to be fully understood, mainly because of the lack of a good approach to evaluate the dynamic changes of heterogeneous macrophages in their residing microenvironment. Here, we report an approach of using antibiofouling PEG-

Indexed as

iron oxide nanoparticlesM2 tumor-associated macrophagemagnetic resonance imagingmannose receptortumor microenvironment

Identifiers

PMID34841220
PMCPMC8626204
OpenAlexW3034750697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.