Evidence map›Paper›PMID 34841218›Full record

ArticlePRiMER (Leawood, Kan.)2021

Deprescribing Inappropriate Proton Pump Inhibitors in a Family Medicine Residency Practice Office.

Andrew Lai, Amy Odom, Steven E Roskos, Julie P Phillips

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in PRiMER (Leawood, Kan.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06858384 (From Awareness to Action), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06858384 narecruitingnot on this mapstarted 2025, after this paper: background citation

From Awareness to Action: Transforming Proton Pump Inhibitor Use in Ras Al Khaimah Through Education and Intervention: the RAK -PRIDE Study

TypeinterventionalSponsorRAK Medical and Health Sciences UniversityRan2025 to 2026Enrolled479ConditionsProton Pump Inhibitors, Deprescribing, Inappropriate UseArmsControl (Standard treatment), Pharmacist-Led Educational Intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Proton Pump Inhibitor Deprescription Prospective Study in Patients Without Indication: Are There Differences in Proportion of Restarts According to Withdrawal Strategy?The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2023
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Andrew LaiSparrow Hospital-Michigan State University Family Medicine Residency Program, Lansing, MI.
Amy OdomSparrow Hospital-Michigan State University Family Medicine Residency Program, Lansing, MI.
Steven E RoskosMichigan State University College of Human Medicine and Sparrow Hospital-Michigan State University Family Medicine Residency Program, Lansing, MI.
Julie P PhillipsMichigan State University College of Human Medicine and Sparrow Hospital-Michigan State University Family Medicine Residency Program, Lansing, MI.
Sparrow Hospital · USMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionProton pump inhibitors (PPIs) are often prescribed beyond their medically-approved duration of use. Long-term PPI use has been linked with numerous adverse effects and contributes to polypharmacy. This study sought to understand the effect of evidence-based education to resident and faculty physicians on deprescribing inappropriate PPIs. We hypothesized that this educational intervention would result in fewer inappropriate PPI prescriptions.

methodsWe performed a chart review on all adult patients in a family medicine residency program practice, identifying those inappropriately taking PPIs. All physicians in the practice participated in an educational intervention regarding deprescribing inappropriate PPIs and were given frequent reminders to continue their deprescribing efforts. We reviewed charts at the end of the study to identify patients with successful deprescribing attempts.

resultsOf the 187 patients prescribed inappropriate PPIs in the study, 100 remained on PPIs at the end of the study (46.6% success rate). There was a significant decrease in the number of patients inappropriately prescribed PPIs by each physician over the course of the study, from a mean of 17.0 (beginning) to 9.1 (end).

conclusionPhysician education with reminders is an effective means of reducing the number of inappropriate PPIs prescribed in a family medicine residency practice. Future studies could investigate the effectiveness of educational interventions with other medication classes that are often prescribed inappropriately.

Identifiers

PMID34841218
PMCPMC8612589
OpenAlexW3210583660

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.