Evidence map›Paper›PMID 34841172›Full record

ArticleACS omega2021

Impedimetric Sensors for Cyclocreatine Phosphate Determination in Plasma Based on Electropolymerized Poly(

Ibrahim F Abo-Elmagd, Amr M Mahmoud, Medhat A Al-Ghobashy, Marianne Nebsen, Nesrine S El Sayed, Shahira Nofal, Sameh H Soror, Robert Todd, Salwa A Elgebaly

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ibrahim F Abo-ElmagdBioanalysis Research Group, School of Pharmacy, Newgiza University, Giza 12256, Egypt.ORCID https://orcid.org/0000-0002-9291-3055
Amr M MahmoudAnalytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID https://orcid.org/0000-0002-7804-6442
Medhat A Al-GhobashyBioanalysis Research Group, School of Pharmacy, Newgiza University, Giza 12256, Egypt.ORCID https://orcid.org/0000-0002-3270-6804
Marianne NebsenAnalytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID https://orcid.org/0000-0002-0687-2358
Nesrine S El SayedDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Shahira NofalDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Ain Helwan, Helwan, Cairo 11795, Egypt.
Sameh H SororDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ain Helwan, Helwan, Cairo 11795, Egypt.
Robert ToddProChem International, LLC, Sheboygan, Wisconsin 53085-3325, United States.
Salwa A ElgebalyNour Heart, Inc., Vienna, Virginia 22180, United States.
Cairo University · EGHelwan University · EGUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclocreatine and its water-soluble derivative, cyclocreatine phosphate (CCrP), are potent cardioprotective drugs. Based on recent animal studies, CCrP, FDA-awarded Orphan Drug Designation, has a promising role in increasing the success rate of patients undergoing heart transplantation surgery by preserving donor hearts during transportation and improving the recovery of transplanted hearts in recipient patients. In addition, CCrP is under investigation as a promising treatment for creatine transporter deficiency, an X-linked inborn error resulting in a poor quality of life for both the patients and the caregiver. A newly designed molecularly imprinted polymer (MIP) material was fabricated by the anodic electropolymerization of

Identifiers

PMID34841172
PMCPMC8613875
OpenAlexW3213309180

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.