Evidence map›Paper›PMID 34841045›Full record

ArticleAAPS open2021

Designing an ideal alcohol-based hand sanitizer: in vitro antibacterial responses of ethanol and isopropyl alcohol solutions to changing composition.

Ifeanyi T Nzekwe, Onyedika I Agwuka, Moses U Okezie, Daniel O Fasheun, Petra O Nnamani, Chukwuma O Agubata

Open access · goldAbstract read
In one paragraph

Article in AAPS open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ifeanyi T NzekweDepartment of Pharmaceutics & Pharmaceutical Technology, Nnamdi Azikiwe University, Awka, Anambra Nigeria.ORCID 0000-0003-0039-8103
Onyedika I AgwukaDepartment of Pharmaceutics & Pharmaceutical Technology, Nnamdi Azikiwe University, Awka, Anambra Nigeria.
Moses U OkezieDepartment of Pharmaceutical Microbiology & Biotechnology, Nnamdi Azikiwe University, Awka, Anambra Nigeria.
Daniel O FasheunDepartment of Biochemistry, Institute of Chemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Petra O NnamaniDepartment of Pharmaceutics, University of Nigeria, Nsukka, Enugu Nigeria.
Chukwuma O AgubataDepartment of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nsukka, Enugu State Nigeria.
Nnamdi Azikiwe University · NGUniversity of Nigeria · NGUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to achieve an in vitro quantification of the effects of composition and formulation factors on the killing rates of alcohol-based hand sanitizers. The killing rates of 85% ethyl alcohol (ET) and isopropyl alcohol (IPA) were studied under different conditions such as pH, electrolyte concentration, or inclusion of herbal extracts (cucumber, carrot, and aloe vera), a quaternary ammonium compound, or thickener over different time intervals. Changes in the activities were retested after 3 months as an indication of stability. From two-way ANOVA, both the time of exposure and the sanitizer type affected the activity against SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41120-021-00038-x.

Indexed as

AdditivesAlcoholDisinfectionSanitizerStability

Identifiers

PMID34841045
PMCPMC8606244
OpenAlexW3216364395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.