Evidence map›Paper›PMID 34840975›Full record

ReviewBioMed research international2021

The Significance of Autoantibodies in Juvenile Dermatomyositis.

Dominika Kwiatkowska, Adam Reich

Abstract readReview
In one paragraph

Review in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Research progress on the dermatomyositis specific autoantibodies and malignancy associated dermatomyositis.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dominika KwiatkowskaDepartment of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland.ORCID https://orcid.org/0000-0003-3268-012X
Adam ReichDepartment of Dermatology, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszów, Poland.ORCID https://orcid.org/0000-0002-5573-1754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Juvenile dermatomyositis is a chronic and rare autoimmune disorder classified into the spectrum of idiopathic inflammatory myopathies. Although this entity is mainly characterized by the presence of pathognomonic cutaneous lesions and proximal muscle weakness, the clinical manifestation can be highly heterogeneous; thus, diagnosis might be challenging. Current treatment recommendations for juvenile dermatomyositis, based mainly upon case series, include the use of corticosteroids, immunomodulatory, and immunosuppressive agents. Recently, several specific autoantibodies have been shown to be associated with distinct clinical phenotypes of classic dermatomyositis. There is a need to further evaluate their relevance in the formation of various clinical features. Furthermore, while providing more personalized treatment strategies, one should consider diversity of autoantibody-related subgroups of juvenile dermatomyositis.

Indexed as

Adenosine TriphosphatasesAmino Acyl-tRNA SynthetasesAntibody SpecificityAutoantibodiesAutoantigensChildDermatomyositisDNA-Binding ProteinsFemaleHumansHydroxymethylglutaryl CoA ReductasesInterferon-Induced Helicase, IFIH1MalePhenotypePrognosisSignal Recognition ParticleAdenosine TriphosphatasesAmino Acyl-tRNA SynthetasesAutoantibodiesAutoantigensDNA-Binding ProteinsHMGCR protein, humanHydroxymethylglutaryl CoA ReductasesIFIH1 protein, humanInterferon-Induced Helicase, IFIH1Mi-2 antibodiesMORC3 protein, humanSignal Recognition ParticleSmall Ubiquitin-Related Modifier ProteinsTranscription FactorsTRIM33 protein, human

Identifiers

PMID34840975
PMCPMC8626176

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.