Evidence map›Paper›PMID 34840887›Full record

ReviewNeurology. Clinical practice2021

Acute Bilateral Blindness in the Setting of Sudden Onset of Bilateral Proptosis and Ophthalmoplegia: A Case Report With Literature Review.

Sara Zarei, Phuong Vo, Christian Sam, Robert W Crow, Charles Stout, Lama Al-Khoury

Open access · greenAbstract readReview
In one paragraph

Review in Neurology. Clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Case of Optic Chiasm Stroke, A Condition Rarely Described in the Literature.European journal of case reports in internal medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sara ZareiDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.
Phuong VoDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.
Christian SamDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.
Robert W CrowDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.
Charles StoutDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.
Lama Al-KhouryDepartment of Neurology (SZ, LAK), HCA Healthcare, Nashville, TN; Riverside Community Hospital (SZ, CS), CA; School of Medicine (PV, CS), UCR, Riverside, CA; Department of Ophthalmology (RWC), UCI, Irvine, CA; and Department of Interventional Neurology (CS), HCA Healthcare, Nashville, TN.ORCID 0000-0001-8041-7487
University of California, Riverside · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAcute bilateral blindness has an extensive differential diagnosis that requires a careful history and physical examination to narrow down. In this article, we discuss the pathophysiology and radiographic findings of each possible diagnosis for acute bilateral blindness. RECENT

findingsVisual pathology with respect to bilateral blindness can be broadly broken down into 3 anatomic categories: media (i.e., the anterior and posterior chamber of the eye), retina, and neural visual pathway. Possible causes of rapid onset bilateral blindness include bilateral occipital infarcts, endogenous bacterial endophthalmitis, orbital cellulitis, orbital compartment syndrome, cavernous sinus thrombophlebitis, thyroid disease, and bilateral nonarteritic ischemic optic neuropathy. SUMMARY: In this case, we present a patient with acute onset of bilateral blindness, in addition to bilateral ophthalmoplegia, proptosis, and orbital chemosis. We believe that this rare case of acute bilateral blindness is thought provoking and aids in the understanding of the differential diagnosis and underlying pathophysiology of visual loss.

Identifiers

PMID34840887
PMCPMC8610505
OpenAlexW3153335082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.