Evidence map›Paper›PMID 34840678›Full record

ArticleJournal of ophthalmic & vision research

Association of

Wafaa Meteoukki, Mostefa Fodil, Nawel Adda Negaz, Nesrine Rahmoun, Sarah Lardjam Hetraf, Hadjira Ouhaibi Djellouli, Ahlem Djelti Messal, Meriem Abdi, Meriem Samia Aberkane, Abdelillah Chiali and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmic & vision research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Systemic Associations with Keratoconus.Life (Basel, Switzerland) · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Wafaa MeteoukkiLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.ORCID https://orcid.org/0000-0001-9821-5808
Mostefa FodilAgence Thématique de Recherche en Sciences de la Santé (ATRSS)- Oran, Algérie.
Nawel Adda NegazAgence Thématique de Recherche en Sciences de la Santé (ATRSS)- Oran, Algérie.
Nesrine RahmounLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Sarah Lardjam HetrafLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Hadjira Ouhaibi DjellouliLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Ahlem Djelti MessalLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Meriem AbdiLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Meriem Samia AberkaneLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Abdelillah ChialiClinique Chiali, Oran, Algérie.
Amine DerdourLaboratoire de Génétique Médicale Appliquée à l'Ophtalmologie, Clinique Hammou Boutlélis Oran, Algérie.
Aicha IdderAgence Thématique de Recherche en Sciences de la Santé (ATRSS)- Oran, Algérie.
Faouzia Zemani -FodilLaboratoire de Génétique Moléculaire et Cellulaire (LGMC), Université des Sciences et de la Technologie d'Oran Mohamed BOUDIAF- USTO-MB, BP 1505, El M'naouer, 31000 Oran, Algérie.
Université des Sciences et de la Technologie d'Oran Mohamed Boudiaf · DZUniversité Oran 1 Ahmed Ben Bella · DZLaboratoire de Génétique Médicale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this case-control study was to determine the impact of environmental factors on the predisposition to develop keratoconus in a sample of Western Algerian population. Subsequently, we were interested in the implication of two single nucleotide polymorphisms (SNPs)

methodsThe study included 70 unrelated KC cases and 70 controls originating from Western Algeria. DNA genotyping was done using predesigned probe-based allelic discrimination TaqManⓇ assays. Allele and genotype frequencies were compared between the cases and controls by Chi-square test and odds ratios with 95% confidence intervals.

resultsA significant association between risk factors such as family history, atopy, eye rubbing, and the development of keratoconus was found in our sample. Smoking would provide a protective effect against the pathology. No statistically significant differences were found in the allele and genotype frequencies between cases and controls neither for

conclusionOur study provides, for the first time, a clear demonstration of the absence of association of the allergy-associated

Indexed as

Case–Control StudyFOXP3 GeneIL4 GeneKeratoconusPolymorphismsWestern Algeria

Identifiers

PMID34840678
PMCPMC8593538
OpenAlexW3210225241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.