ReviewThe Journal of clinical and aesthetic dermatology2021
Natural Cosmeceutical Ingredients for the Management of Hyperpigmentation in Hispanic and Latino Women.
Review in The Journal of clinical and aesthetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 9 citations in OpenAlex.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisorders of hyperpigmentation, such as melasma, postinflammatory pigmentary alteration, and lentigines, pose significant cosmetic concerns for women of Hispanic or Latino race and ethnicity. Natural ingredients are gaining popularity as alternative, safe, and effective topical depigmenting agents.
objectiveWe sought to review clinical studies evaluating the use of natural ingredients in the topical management of hyperpigmentation in Hispanic and Latino women.
methodsWe conducted a systematic review of scientific and medical electronic databases to identity randomized controlled trials (RCTs) and nonrandomized reports on topical natural agents for the treatment of disorders of hyperpigmentation, using Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines.
resultsOur review of the literature revealed relatively few (N=7) clinical studies (including six RCTs) that evaluated the topical management of hyperpigmentation using natural ingredients with specific reference to women of Hispanic or Latino race and ethnicity. Despite limited research data, a small number (N=7) of natural ingredients demonstrated efficacy and safety as depigmenting agents in this cohort, including niacinamide, soy, azelaic acid, ascorbic acid, licorice, emblica, and belides.
conclusionSeveral natural ingredients have scientific data supporting their potential efficacy as topical treatments for disorders of hyperpigmentation in women of Hispanic or Latino race and ethnicity. However, the paucity of robust cosmetic trials in this setting reflects the generalized low representation of Hispanic and Latino individuals in clinical studies of other skin conditions. Many
Indexed as
Identifiers
34840659PMC8570660W3217690561What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.