ArticleDisease markers2021
Association between Iris Biological Features and Corneal Biomechanics in Myopic Eyes.
Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed.
- Scheimpflug Photography-Based Evaluation of Structural Iris Changes Across Keratoconus Stages in Comparison with Healthy Eyes.Ophthalmology and therapy · 2026Article
- Clinical characteristics and risk factors of ocular hypertension: a case-control study.BMC ophthalmology · 2025Article
- Social behavioral analysis of the influence of residential area and grade on pupils' myopia rate: a cross-sectional survey in Nanjing, China.Frontiers in medicine · 2025Article
- Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes.Investigative ophthalmology & visual science · 2023Article
- Association of Iris Structural Measurements with Corneal Biomechanics in Myopic Eyes.Disease markers · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIris biological features such as surface features and profile characteristics reflected the development of iris stroma and microvessels. Iris vessels and microcirculation are still lack of effective detection methods, and we can directly observe only the iris surface biological characteristics. This cross-sectional study evaluated the association between iris surface biological features and corneal biomechanics in young adults with myopia.
methodsWe recruited 152 patients with myopia aged ≥18 years, from the Eye Hospital of Wenzhou Medical University, who had complete Corneal Visualization Scheimpflug Technology (Corvis ST) data and graded iris surface features. Iris surface features included crypts, furrows, and color measured from digital slit lamp images. The biomechanical properties of the cornea were assessed using Corvis ST. Only 1 eye of each participant was randomly selected for analysis. Associations between the iris surface features and corneal biomechanics were analyzed using linear regression models. The grade of iris crypts, furrows, and color and corneal biomechanical parameters measured with Corvis ST was the main outcome measures.
resultsThe iris crypts were significantly associated with deflection amplitude at the first applanation (A1 DLA,
conclusionsIris surface features were associated with corneal biomechanical properties in myopic eyes; more iris crypts were associated with lower corneal stiffness while more extensive furrows were related with higher corneal stiffness. Iris crypts and furrows may provide useful information on corneal biomechanical properties in myopic eyes.
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