Evidence map›Paper›PMID 34840498›Full record

ArticleBulletin of the National Research Centre2021

Phylogenetic and full-length genome mutation analysis of SARS-CoV-2 in Indonesia prior to COVID-19 vaccination program in 2021.

Reviany V Nidom, Setyarina Indrasari, Irine Normalina, Astria N Nidom, Balqis Afifah, Lestari Dewi, Andra K Putra, Arif N M Ansori, Muhammad K J Kusala, Mohammad Y Alamudi and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Bulletin of the National Research Centre, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Reviany V NidomCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Setyarina IndrasariCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Irine NormalinaCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Astria N NidomCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Balqis AfifahCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Lestari DewiFaculty of Medicine, Universitas Hang Tuah, Surabaya, Indonesia.
Andra K PutraDr. Ramelan Naval Hospital, Surabaya, Indonesia.
Arif N M AnsoriCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Muhammad K J KusalaCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Mohammad Y AlamudiCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Chairul A NidomCoronavirus and Vaccine Formulation Research Group, Professor Nidom Foundation, Surabaya, Indonesia.
Airlangga University · IDMinistry of Education and Culture · IDUniversitas Hang Tuah · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndonesia has started the big project of COVID-19 vaccination program since 13 January 2021 by employing the first shot of vaccine to the President of Indonesia as the outbreak and rapid transmission of COVID-19 have endangered not only Indonesian but the global health and economy. This study aimed to investigate the full-length genome mutation analysis of 166 Indonesian SARS-CoV-2 isolates as of 12 January 2021.

resultsAll data of the isolates were extracted from the Global Initiative on Sharing All Influenza Data (GISAID) EpiCoV database. CoVsurver platform was employed to investigate the full-length genome mutation analysis of all isolates. This study also focused on the phylogeny analysis in unlocking the mutation of S protein in Indonesian SARS-CoV-2 isolates. WIV04 isolate that was originated from Wuhan, China was used as the virus reference according to the CoVsurver default. The result showed that a full-length genome mutation analysis of 166 Indonesian SARS-CoV-2 isolates was successfully generated. Every single mutation in S protein was described and then visualized by utilizing BioRender platform. Furthermore, it also found that D614G mutation appeared in 103 Indonesian SARS-CoV-2 isolates.

conclusionsTo sum up, this study helped to observe the spread of COVID-19 transmission. However, it also proposed that the epidemiological surveillance and genomics studies might be improved on COVID-19 pandemic in Indonesia. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42269-021-00657-0.

Indexed as

COVID-19Genome analysisIndonesiaSARS-CoV-2Spike protein

Identifiers

PMID34840498
PMCPMC8606223
OpenAlexW3214914648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.