Evidence map›Paper›PMID 34840383›Full record

Observational studyIranian journal of medical sciences2021

Risk Factors Associated with Long COVID Syndrome: A Retrospective Study.

Ali Akbar Asadi-Pooya, Ali Akbari, Amir Emami, Mehrzad Lotfi, Mahtab Rostamihosseinkhani, Hamid Nemati, Zohreh Barzegar, Maryam Kabiri, Zahra Zeraatpisheh, Mohsen Farjoud-Kouhanjani and 6 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Iranian journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 7 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 7 syntheses or guidelines pooled it, 127 citations in OpenAlex.

  1. Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence.Archives of public health = Archives belges de sante publique · 2025
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  7. Clinical patterns of somatic symptoms in patients suffering from post-acute long COVID: a systematic review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 2 countries.

Ali Akbar Asadi-PooyaEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali AkbariDepartment of Anesthesiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Amir EmamiBurn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mehrzad LotfiMedical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahtab RostamihosseinkhaniEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Hamid NematiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Zohreh BarzegarEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Maryam KabiriEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Zahra ZeraatpishehEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohsen Farjoud-KouhanjaniEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Anahita JafariEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Fateme SasanniaEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shayan AshrafiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Masoume NazeriEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Sara NasiriEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mina ShahisavandiEpilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recently, people have recognized the post-acute phase symptoms of the COVID-19. We investigated the long-term symptoms associated with COVID-19, (Long COVID Syndrome), and the risk factors associated with it. Methods: This was a retrospective observational study. All the consecutive adult patients referred to the healthcare facilities anywhere in Fars province from 19 February 2020 until 20 November 2020 were included. All the patients had a confirmed COVID-19 diagnosis. In a phone call to the patients, at least three months after their discharge from the hospital, we obtained their current information. The IBM SPSS Statistics (version 25.0) was used. Pearson Chi square, Fisher's exact test, Results: In total, 4,681 patients were studied, 2915 of whom (62.3%) reported symptoms. The most common symptoms of long COVID syndrome were fatigue, exercise intolerance, walking intolerance, muscle pain, and shortness of breath. Women were more likely to experience long-term COVID syndrome than men (Odds Ratio: 1,268; 95% Confidence Interval: 1,122-1,432; P=0.0001), which was significant. Presentation with respiratory problems at the onset of illness was also significantly associated with long COVID syndrome (Odds Ratio: 1.425; 95% Confidence Interval: 1.177-1.724; P=0.0001). A shorter length of hospital stay was inversely associated with long COVID syndrome (Odds Ratio: 0.953; 95% Confidence Interval: 0.941-0.965; P=0.0001). Conclusion: Long COVID syndrome is a frequent and disabling condition and has significant associations with sex (female), respiratory symptoms at the onset, and the severity of the illness.

Indexed as

AdultCOVID-19FemaleHumansIranMalePost-Acute COVID-19 SyndromeRetrospective StudiesRisk FactorsCOVID-19MedicineSARS-CoV-2Viruses

Identifiers

PMID34840383
PMCPMC8611223
OpenAlexW3206121607

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.