Evidence map›Paper›PMID 34840123›Full record

ReviewBrazilian journal of otorhinolaryngology

Ectopic thymic tissue in subglottis of children: evaluation and management.

Yihang Lin, Junyang Li, Lianyan Xue, Peixuan Sun, Qiao He, Youjin Li

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yihang LinShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Otolaryngology-Head & Neck Surgery, Shanghai, China.
Junyang LiShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Otolaryngology-Head & Neck Surgery, Shanghai, China.
Lianyan XueShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Radiology, Shanghai, China.
Peixuan SunShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Diagnostic Imaging Center, Shanghai, China.
Qiao HeShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Pathology, Shanghai, China.
Youjin LiShanghai Jiaotong University, School of Medicine, Shanghai Children's Medical Center, Department of Otolaryngology-Head & Neck Surgery, Shanghai, China. Electronic address: kevinliyoujin@outlook.com.
Shanghai Children's Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEctopic thymic tissue in the subglottis is an extremely rare disease that causes airway obstruction. Few cases reported were accurately diagnosed before surgery.

methodsA case of a 2-year-old boy with airway obstruction caused by a left subglottic mass was reported. The presentation of radiological imaging, direct laryngoscopy and bronchoscopy, pathology, and surgical management were reviewed. An extensive search in PubMed, EMBASE, Web of Science, Google Scholar, and EBSCO of English literature was performed without a limit of time.

resultsBesides our case, only six cases were reported since 1987. The definitive diagnosis on these patients were made with the findings of pathology, of which, five were ectopic thymus and two were ectopic thymic cysts. Our case was the only one with a correct suspicion preoperatively. Four cases underwent open surgical resection, and two cases underwent microlaryngeal surgery, while one deceased after emergency tracheostomy. No recurrences were found by six patients during the follow-up after successful treatments.

conclusionEctopic thymus is a rare condition, infrequently considered in the differential diagnosis of subglottic masses. Modified laryngofissure may be an effective approach to removing the subglottic ectopic thymus and reconstructing the intact subglottic mucosa.

Indexed as

Airway ObstructionLaryngeal DiseasesLarynxChildChild, PreschoolDiagnosis, DifferentialHumansLaryngoscopyMaleCongenital anomalyEctopic thymusSubglottis

Identifiers

PMID34840123
PMCPMC9874344
OpenAlexW3211717200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.