ReviewNeuroscience and biobehavioral reviews2022
FACTORS CONTRIBUTING TO THE ESCALATION OF ALCOHOL CONSUMPTION.
Review in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Gender differences in changes in alcohol consumption achieved by free provision of non-alcoholic beverages: a secondary analysis of a randomized controlled trial.BMC public health · 2024Trial
- Cued unpredictable intermittent access exacerbates loss of control over ethanol drinking.Neuropharmacology · 2026Article
- Alexithymia mediates white-matter microstructure and substance use escalation in trauma-exposed individuals.Journal of affective disorders · 2026Article
- Individualized assignment to short-term alcohol abstinence: A proof-of-concept human laboratory study using psychopathology dimensions.Drug and alcohol dependence reports · 2026Article
- Cued unpredictable intermittent access exacerbates loss of control over ethanol drinking.bioRxiv : the preprint server for biology · 2026Article
- A prospective co-twin control analysis of internalizing and externalizing pathways for alcohol, nicotine, and cannabis use problems from adolescence through adulthood.Psychological medicine · 2026Article
- Modeling escalation of drug intake to identify molecular targets for treating substance use disorders: A slippery slope upward.Neuroscience and biobehavioral reviews · 2025Review
- Promising strategies for the prevention of alcohol-related brain damage through optimised management of acute alcohol withdrawal: A focussed literature review.Journal of psychopharmacology (Oxford, England) · 2025Review
- Evaluating the association between alcohol sweetness preference, alcohol harm, and alcohol value.Experimental and clinical psychopharmacology · 2025Article
- Validation of a Questionnaire of Motivations for Moderated and Severe Alcohol Consumption Among College Students.Healthcare (Basel, Switzerland) · 2025Article
- Risk factors for relapse among patients with alcohol dependence syndrome.Bioinformation · 2025Article
- Association Between GABRG2 and Self-Rating of the Effects of Alcohol in a French Young Adult Sample.Risk management and healthcare policy · 2025Article
- Chronic Low Back Pain Causal Risk Factors Identified by Mendelian Randomization: a Cross-Sectional Cohort Analysis.medRxiv : the preprint server for health sciences · 2024Article
- Identification of Phosphodiesterase-7A (PDE7A) as a Novel Target for Reducing Ethanol Consumption in Mice.The international journal of neuropsychopharmacology · 2024Article
- Effects of CB1 receptor negative allosteric modulator Org27569 on oxycodone withdrawal symptoms in mice.Psychopharmacology · 2024Article
- Prior experience with flavored alcohol increases preference for flavored alcohol but flavor does not influence binge-like drinking behavior in mice.Physiology & behavior · 2023Article
- Article
- Conditioned stimulus effects on paired or alternative reinforcement depend on presentation duration: Implications for conceptualizations of craving.Frontiers in behavioral neuroscience · 2022Article
- Genetic Variability of Incretin Receptors and Alcohol Dependence: A Pilot Study.Frontiers in molecular neuroscience · 2022Article
- Incorporating Mental Health Into Lifestyle Medicine.American journal of lifestyle medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Understanding factors that contribute to the escalation of alcohol consumption is key to understanding how an individual transitions from non/social drinking to AUD and to providing better treatment. In this review, we discuss how the way ethanol is consumed as well as individual and environmental factors contribute to the escalation of ethanol consumption from intermittent low levels to consistently high levels. Moreover, we discuss how these factors are modelled in animals. It is clear a vast array of complex, interacting factors influence changes in alcohol consumption. Some of these factors act early in the acquisition of ethanol consumption and initial escalation, while others contribute to escalation of ethanol consumption at a later stage and are involved in the development of alcohol dependence. There is considerable need for more studies examining escalation associated with the formation of dependence and other hallmark features of AUD, especially studies examining mechanisms, as it is of considerable relevance to understanding and treating AUD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.